Susceptibility of solid organ transplant recipients to viral pathogens with zoonotic potential: A mini-review.
| Autor: | Bezerra KC; Universidade Federal do Ceará, Faculdade de Medicina, Laboratório da Biologia da Cicatrização, Ontogenia e Nutrição de Tecidos, Fortaleza, CE, Brazil., Vieira CMAG; Universidade Federal do Ceará, Faculdade de Medicina, Laboratório da Biologia da Cicatrização, Ontogenia e Nutrição de Tecidos, Fortaleza, CE, Brazil., de Oliveira-Filho EF; Charité-Universitätsmedizin Berlin, Institute of Virology, Berlin, Germany., Reis CRS; Fundação Oswaldo Cruz, Instituto Aggeu Magalhães, Departamento de Microbiologia, Recife, PE, Brazil., Oriá RB; Universidade Federal do Ceará, Faculdade de Medicina, Laboratório da Biologia da Cicatrização, Ontogenia e Nutrição de Tecidos, Fortaleza, CE, Brazil. Electronic address: oria@ufc.br. |
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| Jazyk: | angličtina |
| Zdroj: | The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases [Braz J Infect Dis] 2024 Mar-Apr; Vol. 28 (2), pp. 103742. Date of Electronic Publication: 2024 Apr 23. |
| DOI: | 10.1016/j.bjid.2024.103742 |
| Abstrakt: | A substantial number of zoonotic diseases are caused by viral pathogens, representing a significant menace to public health, particularly to susceptible populations, such as pregnant women, the elderly, and immunocompromised individuals. Individuals who have undergone solid organ transplantation frequently experience immunosuppression, to prevent organ rejection, and, thus are more prone to opportunistic infections. Furthermore, the reactivation of dormant viruses can threaten transplant recipients and organ viability. This mini-review examines the up-to-date literature covering potential zoonotic and organ rejection-relevant viruses in solid organ transplant recipients. A comprehensive list of viruses with zoonotic potential is highlighted and the most important clinical outcomes in patients undergoing transplantation are described. Moreover, this mini-review calls attention to complex multifactorial events predisposing viral coinfections and the need for continuous health surveillance and research to understand better viral pathogens' transmission and pathophysiology dynamics in transplanted individuals. Competing Interests: Conflicts of interest The authors declare no have conflicts of interest. (Copyright © 2024. Published by Elsevier España, S.L.U.) |
| Databáze: | MEDLINE |
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