An electrochemiluminescence sensor based on Ag NPs amplifying PDDA-modified TbPO 4 :Ce NWs signal for sensitive detection of lincomycin.

Autor: Zhi J; Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China., Wang W; Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China; Analysis and Testing Center, NERC Biomass of Changzhou University, Jiangsu 213032, China. Electronic address: king717@cczu.edu.cn., Mei X; Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China., Li Q; Changzhou High-Tech Industry Development Zone Sanwei Industrial Technology Research Instit Co., Ltd, Changzhou 213164, China., Jiang D; Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China., Shan X; Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China., Chen X; School of Chemistry and Material Engineering, Changzhou Institute of Technology, Changzhou 213032, China., Chen Z; Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China. Electronic address: zdchen@cczu.edu.cn.
Jazyk: angličtina
Zdroj: Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2024 Aug; Vol. 158, pp. 108702. Date of Electronic Publication: 2024 Apr 02.
DOI: 10.1016/j.bioelechem.2024.108702
Abstrakt: The residue of lincomycin in water will not only aggravate the drug resistance of bacteria but also cause damage to the human body through biological accumulation. In this work, an electrochemiluminescence (ECL) aptasensor for the detection of lincomycin was constructed based on polydimethyldiallylammonium chloride (PDDA) functionalized Ce-doped TbPO 4 nanowires (PDDA-TbPO 4 :Ce NWs) and silver nanoparticles (Ag NPs). TbPO 4 :Ce NWs were used as the luminophore, and PDDA was used to functionalize the luminophore to make the surface of the luminophore positively charged. The negatively charged silver nanoparticles were combined with PDDA-TbPO 4 :Ce NWs by electrostatic interaction. Ag NPs accelerated the electron transfer rate and promoted the ECL efficiency, which finally increased the ECL intensity of TbPO 4 :Ce NWs by about 4 times. Under the optimal conditions, the detection limit of the ECL sensor was as low as 4.37 × 10 -16 M, and the linear range was 1 × 10  - 15 M to 1 × 10  - 5 M, with good selectivity, stability, and repeatability. The sensor can be applied to the detection of lincomycin in water, and the recovery rate is 97.7-103.4 %, which has broad application prospects.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier B.V.)
Databáze: MEDLINE
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