| Autor: |
Salawudeen A, Soule G, Tailor N, Klassen L, Audet J, Sloan A, Deschambault Y, Safronetz D |
| Jazyk: |
angličtina |
| Zdroj: |
Emerging infectious diseases [Emerg Infect Dis] 2024 May; Vol. 30 (5), pp. 1004-1008. |
| DOI: |
10.3201/eid3005.231248 |
| Abstrakt: |
We evaluated the in vitro effects of lyophilization for 2 vesicular stomatitis virus-based vaccines by using 3 stabilizing formulations and demonstrated protective immunity of lyophilized/reconstituted vaccine in guinea pigs. Lyophilization increased stability of the vaccines, but specific vesicular stomatitis virus-based vaccines will each require extensive analysis to optimize stabilizing formulations. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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