Optic neuritis and mydriasis after vaccination: a case report.

Autor: Bonamigo EL; University of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil. elcio.bonamigo@unoesc.edu.br., Kuyava P; University of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil., Reginatto TSPZ; University of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil., Duran AG; University of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil., Truculo L; University of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil., Rossi EE; Unochapecó. Street Senador Atílio Fontana, 591-E, Neighborhood Efapi, Chapecó, Santa Catarina, 89600-000, Brazil., Stock RA; University of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil., Grasel CE; University of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil.
Jazyk: angličtina
Zdroj: Journal of medical case reports [J Med Case Rep] 2024 Apr 25; Vol. 18 (1), pp. 223. Date of Electronic Publication: 2024 Apr 25.
DOI: 10.1186/s13256-024-04526-y
Abstrakt: Background: Optic neuritis (ON) is an inflammatory demyelinating condition of the optic nerve, with various causes. Its incidence is higher in children and young adults than in older adults of both genders, but is more common in women than in men. ON is rarely associated with mydriasis, and it is seldom triggered by vaccines against tetanus and diphtheria.
Case Report: A 36-year-old Caucasian woman presented with bilateral ON that had started 18 days after administration of a booster dose of the double adult vaccine (dT) against diphtheria and tetanus. Bilateral mydriasis persisted after treatment and clinical resolution of the ON. She experienced severe headache, blurred vision, decreased visual acuity in the right eye and bilateral mydriasis, a diagnosis confirmed by imaging tests. Treatment with oral corticosteroids resulted in rapid resolution of the neuritis; however, mydriasis persisted for several months.
Conclusion: This study describes a very unusual case of bilateral ON associated with prolonged mydriasis after vaccination against tetanus and diphtheria that regressed after treatment with oral corticosteroids. Prolonged mydriasis was the manifestation that differed from the other cases previously described.
(© 2024. The Author(s).)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje