FeS 2 nanosheets-luminol-O 2 chemiluminescence method for determination of venlafaxine hydrochloride, imipramine hydrochloride, and cefazolin sodium.

Autor: Iranifam M; Department of Chemistry, Faculty of Basic Sciences, University of Maragheh, Maragheh, Iran., Royan M; Department of Chemistry, Faculty of Basic Sciences, University of Maragheh, Maragheh, Iran., Golshani P; Department of Chemistry, Faculty of Basic Sciences, University of Maragheh, Maragheh, Iran., Hassanpour-Khaneghah M; Department of Chemistry, Faculty of Basic Sciences, University of Maragheh, Maragheh, Iran.; Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran., Al Lawati HAJ; Department of Chemistry, College of Science, Sultan Qaboos University, Muscat, Oman.
Jazyk: angličtina
Zdroj: Luminescence : the journal of biological and chemical luminescence [Luminescence] 2024 Apr; Vol. 39 (4), pp. e4745.
DOI: 10.1002/bio.4745
Abstrakt: This study introduces a novel chemiluminescence (CL) approach utilizing FeS 2 nanosheets (NSs) catalyzed luminol-O 2 CL reaction for the measurement of three pharmaceuticals, namely venlafaxine hydrochloride (VFX), imipramine hydrochloride (IPM), and cefazolin sodium (CEF). The CL method involved the phenomenon of quenching induced by the pharmaceuticals in the CL reaction. To achieve the most quenching efficacy of the pharmaceuticals in the CL reaction, the concentrations of reactants comprising luminol, NaOH, and FeS 2 NSs were optimized accordingly. The calibration curves demonstrated exceptional linearity within the concentration range spanning from 4.00 × 10 -7 to 1.00 × 10 -3  mol L -1 , 1.00 × 10 -7 to 1.00 × 10 -4  mol L -1 , and 4.00 × 10 -6 to 2.00 × 10 -4  mol L -1 with detection limits (3σ) of 3.54 × 10 -7 , 1.08 × 10 -8 , and 2.63 × 10 -6  mol L -1 for VFX, IPM, and CEF, respectively. This study synthesized FeS 2 NSs using a facile hydrothermal approach, and then the synthesized FeS 2 NSs were subjected to a comprehensive characterization using a range of spectroscopic methods. The proposed CL method was effective in measuring the aforementioned pharmaceuticals in pharmaceutical formulations as well as different water samples. The mechanism of the CL system has been elucidated.
(© 2024 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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