Temporal stability of tongue microbiota in older patients - A pilot study.

Autor:	Tsai FT; College of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan., Yang CC; College of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Stomatology, Oral & Maxillofacial Surgery, Taipei Veterans General Hospital, Taipei, Taiwan., Lin YC; College of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Oral Medicine Innovation Center (OMIC), National Yang Ming Chiao Tung University, Taipei, Taiwan., Hsu ML; College of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan., Hong G; Division of Craniofacial Development and Tissue Biology, Tohoku University, Senda, Japan., Yang MC; Division of Craniofacial Development and Tissue Biology, Tohoku University, Senda, Japan., Wang DH; College of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Oral Medicine Innovation Center (OMIC), National Yang Ming Chiao Tung University, Taipei, Taiwan., Huang LJ; Department of Dentistry, National Yang Ming Chiao Tung University Hospital, Yilan County, Taiwan., Lin CT; Department of Dentistry, National Yang Ming Chiao Tung University Hospital, Yilan County, Taiwan., Hsu WE; Department of Dentistry, Far Eastern Memorial Hospital, New Taipei City, Taiwan., Tu HF; College of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Dentistry, National Yang Ming Chiao Tung University Hospital, Yilan County, Taiwan.
Jazyk:	angličtina
Zdroj:	Journal of dental sciences [J Dent Sci] 2024 Apr; Vol. 19 (2), pp. 1087-1095. Date of Electronic Publication: 2024 Feb 01.
DOI:	10.1016/j.jds.2024.01.012
Abstrakt:	Background/purpose: Healthy states of human microbiota depend on a stable community of symbiotic microbes irrespective of external challenges from the environment. Thus, long-term stability of the oral microbiota is of importance, particularly for older patient populations. Materials and Methods: We used next-generation sequencing (NGS) to examine the tongue microbiota of 18 individuals receiving long-term care over a 10-month period. Results: Beta diversity analysis demonstrated temporal stability of the tongue microbiota, as microbial compositions from all time points were indistinguishable from each other ( P  = 0.0887). However, significant individual variation in microbial composition ( P  = 0.0001) was observed, underscoring the presence of a unique microbial profile for each patient. Conclusion: The temporal dynamics of tongue microbiota exhibit long-term stability, providing diagnostic implications for oral diseases within older patient populations. Competing Interests: The authors have no conflicts of interest relevant to this article. (© 2024 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V.)
Databáze:	MEDLINE
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