Autor: |
Vassalle C; Department of Laboratory Medicine, Fondazione Toscana Gabriele Monasterio, 56124 Pisa, Italy., Grifoni D; Laboratory of Monitoring and Environmental Modelling for the Sustainable Development (LaMMA Consortium), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy.; Institute of Bioeconomy (IBE), National Research Council (CNR), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy., Gozzini B; Laboratory of Monitoring and Environmental Modelling for the Sustainable Development (LaMMA Consortium), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy.; Institute of Bioeconomy (IBE), National Research Council (CNR), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy., Parlanti A; Diagnostic and Interventional Cardiology Department, Fondazione Toscana Gabriele Monasterio, Ospedale Pasquinucci, 54100 Massa, Italy., Fibbi L; Laboratory of Monitoring and Environmental Modelling for the Sustainable Development (LaMMA Consortium), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy.; Institute of Bioeconomy (IBE), National Research Council (CNR), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy., Marchi F; Diagnostic and Interventional Cardiology Department, Fondazione Toscana Gabriele Monasterio, Ospedale Pasquinucci, 54100 Massa, Italy., Messeri G; Laboratory of Monitoring and Environmental Modelling for the Sustainable Development (LaMMA Consortium), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy.; Institute of Bioeconomy (IBE), National Research Council (CNR), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy., Pylypiv N; Diagnostic and Interventional Cardiology Department, Fondazione Toscana Gabriele Monasterio, Ospedale Pasquinucci, 54100 Massa, Italy., Messeri A; Institute of Bioeconomy (IBE), National Research Council (CNR), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy., Paradossi U; Diagnostic and Interventional Cardiology Department, Fondazione Toscana Gabriele Monasterio, Ospedale Pasquinucci, 54100 Massa, Italy., Berti S; Diagnostic and Interventional Cardiology Department, Fondazione Toscana Gabriele Monasterio, Ospedale Pasquinucci, 54100 Massa, Italy. |
Abstrakt: |
Objectives: To evaluate CV profiles, periprocedural complications, and in-hospital mortality in acute myocardial infarction (AMI) according to climate. Methods: Data from 2478 AMI patients (1779 men; mean age 67 ∓ 13 years; Pasquinucci Hospital ICU, Massa, Italy; 2007-2018) were retrospectively analyzed according to climate (LAMMA Consortium; Firenze, Italy) by using three approaches as follows: (1) annual warm (May-October) and cold (November-April) periods; (2) warm and cold extremes of the two periods; and (3) warm and cold extremes for each month of the two periods. Results: All approaches highlighted a higher percentage of AMI hospitalization for patients with adverse CV profiles in relation to low temperatures, or higher periprocedural complications and in-hospital deaths. In warmer times of the cold periods, there were fewer admissions of dyslipidemic patients. During warm periods, progressive heat anomalies were characterized by more smoker (approaches 2 and 3) and young AMI patient (approach 3) admissions, whereas cooler times (approach 3) evidenced a reduced hospitalization of diabetic and dyslipidemic patients. No significant effects were observed for the heat index and light circulation. Conclusions: Although largely overlapping, different approaches identify patient subgroups with different CV risk factors at higher AMI admission risk and adverse short-term outcomes. These data retain potential implications regarding pathophysiological mechanisms of AMI and its prevention. |