A Retrospective Analysis of 129 Ameloblastoma Cases: Clinical and Demographical Trends from a Single Institution.

Autor: Vila S; Department of Oral & Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, USA., Oster RA; Department of Medicine, University of Alabama at Birmingham, Birmingham, USA., James S; Department of Otolaryngology, University of Alabama at Birmingham, Birmingham, USA., Morlandt AB; Department of Oral & Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, USA., Powell KK; Department of Oral & Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, USA., Amm HM; Department of Oral & Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, USA. hopeamm@uab.edu.
Jazyk: angličtina
Zdroj: Journal of racial and ethnic health disparities [J Racial Ethn Health Disparities] 2024 Apr 12. Date of Electronic Publication: 2024 Apr 12.
DOI: 10.1007/s40615-024-01993-3
Abstrakt: Ameloblastomas are benign neoplasms of the jaw, but frequently require extensive surgery. The aim of the study was to analyze the demographic and clinicopathological features of ameloblastoma cases at a single Oral and Maxillofacial Surgery group in the United States.
Study Design: A retrospective chart review of patients evaluated for ameloblastoma between 2010 and 2020 at a single tertiary care center. Age, race, sex, tumor size, tumor location, and histological subtypes were recorded.
Results: A total of 129 cases of ameloblastoma were recorded with a mean patient age of 42 ± 18.6 years (range 9-91 years old), male to female ratio 1.08:1. Ameloblastoma presenting in the mandible outnumbered maxilla in primary (118 to 8, respectively) and recurrent cases (8 to 1, respectively). There was a higher prevalence of ameloblastoma in Black patients (61.3%) with mean age of Black patients occurring at 40.5 years and the mean age of White patients occurring at 47.8 years and mean tumor size trended larger in the Black patients (15.7 cm 2 ) compared to White patients (11.8 cm 2 ).
Conclusion: Data suggests a strong influence of racial factors on the incidence of ameloblastoma, with regards to size, Black patients with ameloblastoma trended higher and more data is needed to clearly elucidate any relationship between the tumor size and race, as other factors may influence the size (such as time to discovery).
(© 2024. The Author(s).)
Databáze: MEDLINE
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