A Study on Intelligent Optical Bone Densitometry.

Autor:	Meitei TG; Department of PhotonicsCollege of Electrical and Computer EngineeringNational Yang Ming Chiao Tung University Hsinchu 30010 Taiwan., Chang WC; Department of PhotonicsCollege of Electrical and Computer EngineeringNational Yang Ming Chiao Tung University Hsinchu 30010 Taiwan.; Department of Orthopedic SurgeryWan Fang HospitalTaipei Medical University Taipei 110 Taiwan., Cheong PL; Department of PhotonicsCollege of Electrical and Computer EngineeringNational Yang Ming Chiao Tung University Hsinchu 30010 Taiwan.; Department of Biological Science and TechnologyNational Yang Ming Chiao Tung University Hsinchu 30010 Taiwan.; Department of PediatricsNational Taiwan University Hospital Hsinchu Branch Hsinchu 300 Taiwan., Wang YM; Department of PhotonicsCollege of Electrical and Computer EngineeringNational Yang Ming Chiao Tung University Hsinchu 30010 Taiwan., Sun CW; Department of PhotonicsCollege of Electrical and Computer EngineeringNational Yang Ming Chiao Tung University Hsinchu 30010 Taiwan.; Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Yang Ming Chiao Tung University Hsinchu 30010 Taiwan.; Medical Device Innovation and Translation CenterNational Yang Ming Chiao Tung University Taipei City 112 Taiwan.
Jazyk:	angličtina
Zdroj:	IEEE journal of translational engineering in health and medicine [IEEE J Transl Eng Health Med] 2024 Mar 21; Vol. 12, pp. 401-412. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).
DOI:	10.1109/JTEHM.2024.3368106
Abstrakt:	Osteoporosis is a prevalent chronic disease worldwide, particularly affecting the aging population. The gold standard diagnostic tool for osteoporosis is Dual-energy X-ray Absorptiometry (DXA). However, the expensive cost of the DXA machine and the need for skilled professionals to operate it restrict its accessibility to the general public. This paper builds upon previous research and proposes a novel approach for rapidly screening bone density. The method involves utilizing near-infrared light to capture local body information within the human body. Deep learning techniques are employed to analyze the obtained data and extract meaningful insights related to bone density. Our initial prediction, utilizing multi-linear regression, demonstrated a strong correlation (r = 0.98, p-value = 0.003**) with the measured Bone Mineral Density (BMD) obtained from Dual-energy X-ray Absorptiometry (DXA). This indicates a highly significant relationship between the predicted values and the actual BMD measurements. A deep learning-based algorithm is applied to analyze the underlying information further to predict bone density at the wrist, hip, and spine. The prediction of bone densities in the hip and spine holds significant importance due to their status as gold-standard sites for assessing an individual's bone density. Our prediction rate had an error margin below 10% for the wrist and below 20% for the hip and spine bone density. (© 2024 The Authors.)
Databáze:	MEDLINE
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