Evaluating the dynamics of hospital COVID-19 contacts and subsequent conversion to SARS-CoV-2 infection: a multi-centre retrospective cohort study.

Autor:	Okeke N; Directorate of Infection, Guy's and St. Thomas NHS Foundation Trust, St. Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK., Snell LB; Directorate of Infection, Guy's and St. Thomas NHS Foundation Trust, St. Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK., Rathish B; Directorate of Infection, Guy's and St. Thomas NHS Foundation Trust, St. Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK., Hussein A; Directorate of Infection, Guy's and St. Thomas NHS Foundation Trust, St. Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK., Newsholme W; Directorate of Infection, Guy's and St. Thomas NHS Foundation Trust, St. Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK., Mack D; Department of Microbiology, Royal Free Hospital, Royal Free London NHS Foundation Trust, Pond Street NW3 2QG, UK., Breathnach A; Department of Infection, St George's University Hospitals NHS Foundation Trust, Tooting, London SW17 0QT, UK., Otter JA; Directorate of Infection, Guy's and St. Thomas NHS Foundation Trust, St. Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK.; National Institute for Healthcare Research Health Protection Research Unit (NIHR HPRU) in HCAI and AMR, Imperial College London & Public Health England, Hammersmith Hospital, Du Cane Road, W12 0HS, UK.
Jazyk:	angličtina
Zdroj:	Infection prevention in practice [Infect Prev Pract] 2023 Nov 10; Vol. 6 (2), pp. 100325. Date of Electronic Publication: 2023 Nov 10 (Print Publication: 2024).
DOI:	10.1016/j.infpip.2023.100325
Abstrakt:	We investigated the dynamics of COVID-19 contacts subsequent conversion to SARS-CoV-2 infection in an inpatient setting across three National Health Service (NHS) Trusts. 9.2% (476/5,156) COVID-19 contacts met inclusion criteria, were typable and tested positive for COVID-19. There was no significant difference between Omicron and non-Omicron contacts overall conversion proportions. Omicron contacts converted faster than non-Omicron contacts (median 3 days vs 4 days, P =0.03), and had significantly greater proportions of early conversions at day 3, 5, and 7 timepoints. (© 2023 The Authors.)
Databáze:	MEDLINE
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