Multifaceted associations between walking performance, physical fitness, extremity function, health status, and depression in individuals with COPD.

Autor: Aldhahi MI; Department of Rehabilitation Sciences, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., Baattaiah BA; Department of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia., Alharbi MD; Department of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia., Alotaibi M; Department of Rehabilitation, Faculty of Applied Medical Sciences, Northern Border University, Arar, Saudi Arabia., Nazer R; Cardiac Sciences Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Albarrati A; Rehabilitation Sciences Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: Annals of medicine [Ann Med] 2024 Dec; Vol. 56 (1), pp. 2338248. Date of Electronic Publication: 2024 Apr 08.
DOI: 10.1080/07853890.2024.2338248
Abstrakt: Background/objective(s): Chronic obstructive pulmonary disease (COPD) can precipitate a deterioration of an individual's physical performance and overall health. Evidence suggests that, along with pulmonary functions, several other factors are related to the significant impairment of walking performance in individuals with COPD. This study compared the depressive symptoms, health status, upper and lower extremity functions, and peak oxygen uptake (VO 2peak ) in a group of individuals with COPD based on walking performance using a cutoff distance of 350 m in the six-minute walking test (6MWT). The study also investigated the associations between these factors and walking performance.
Materials and Methods: Participants performed the 6MWT according to the guidelines and were classified into high (>350 m; n  = 40) or low (<350 m; n  = 30) walking performance groups according to distance. The forced expiratory volume (FEV1), forced vital capacity (FVC), and FEV1/FVC ratio were recorded. Participants completed the Patient Health Questionnaire-9 (PHQ-9), St. George's Respiratory Questionnaire (SGRQ), and the Upper and Lower Extremity Functional Index (UEFI/LEFI). Predicted VO 2peak was measured using the Duke Activity Status Index (DASI).
Results: Seventy participants with a mean age of 63 ± 11 years (20% female) were enrolled in this study. Patients with high walking performance demonstrated significantly better health status than those with low walking performance (SGRQ: 49 ± 25 vs. 56 ± 21, p  = 0.03). Participants with low walking performance had lower predicted VO 2peak compared to their higher performing counterparts ( p  = 0.002). The overall model was significant (F(8, 61) = 7.48, p  = 0.0006), with PHQ-9, SGRQ, UEFI/LEFI, VO 2peak , and FEV1/FVC explaining approximately 49.5% of the variance in the 6MWT distance.
Conclusion: This study shed light on the association of depressive symptoms, health status, extremity function, and VO 2peak with walking performance, providing valuable insights that may impact the management and care of individuals with COPD.
Databáze: MEDLINE
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