A deep learning approach for fast muscle water T2 mapping with subject specific fat T2 calibration from multi-spin-echo acquisitions.

Autor: Barbieri M; Department of Radiology, Stanford University, Stanford, CA, USA. mb7@stanford.edu., Hooijmans MT; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands., Moulin K; Department of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Cork TE; Department of Radiology, Stanford University, Stanford, CA, USA., Ennis DB; Department of Radiology, Stanford University, Stanford, CA, USA., Gold GE; Department of Radiology, Stanford University, Stanford, CA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA., Kogan F; Department of Radiology, Stanford University, Stanford, CA, USA., Mazzoli V; Department of Radiology, Stanford University, Stanford, CA, USA.; Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, USA.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 Apr 08; Vol. 14 (1), pp. 8253. Date of Electronic Publication: 2024 Apr 08.
DOI: 10.1038/s41598-024-58812-2
Abstrakt: This work presents a deep learning approach for rapid and accurate muscle water T 2 with subject-specific fat T 2 calibration using multi-spin-echo acquisitions. This method addresses the computational limitations of conventional bi-component Extended Phase Graph fitting methods (nonlinear-least-squares and dictionary-based) by leveraging fully connected neural networks for fast processing with minimal computational resources. We validated the approach through in vivo experiments using two different MRI vendors. The results showed strong agreement of our deep learning approach with reference methods, summarized by Lin's concordance correlation coefficients ranging from 0.89 to 0.97. Further, the deep learning method achieved a significant computational time improvement, processing data 116 and 33 times faster than the nonlinear least squares and dictionary methods, respectively. In conclusion, the proposed approach demonstrated significant time and resource efficiency improvements over conventional methods while maintaining similar accuracy. This methodology makes the processing of water T 2 data faster and easier for the user and will facilitate the utilization of the use of a quantitative water T 2 map of muscle in clinical and research studies.
(© 2024. The Author(s).)
Databáze: MEDLINE
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