Motion-Defined Form Perception in Deprivation Amblyopia.

Autor:	Giaschi DE; Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Asare AK; Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Jost RM; Pediatric Vision Laboratory, Retina Foundation of the Southwest, Dallas, Texas, United States., Kelly KR; School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada., Birch EE; Pediatric Vision Laboratory, Retina Foundation of the Southwest, Dallas, Texas, United States.
Jazyk:	angličtina
Zdroj:	Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2024 Apr 01; Vol. 65 (4), pp. 13.
DOI:	10.1167/iovs.65.4.13
Abstrakt:	Purpose: The purpose of this study was to assess motion-defined form perception, including the association with clinical and sensory factors that may drive performance, in each eye of children with deprivation amblyopia due to unilateral cataract. Methods: Coherence thresholds for orientation discrimination of motion-defined form were measured using a staircase procedure in 30 children with deprivation amblyopia and 59 age-matched controls. Visual acuity, stereoacuity, fusion, and interocular suppression were also measured. Fixation stability and fellow-eye global motion thresholds were measured in a subset of children. Results: Motion-defined form coherence thresholds were elevated in 90% of children with deprivation amblyopia when viewing with the amblyopic eye and in 40% when viewing with the fellow eye. The deficit was similar in children with a cataract that had been visually significant at birth (congenital) and in children for whom the cataract appeared later in infancy or childhood (developmental). Poorer motion-defined form perception in amblyopic eyes was associated with poorer visual acuity, poorer binocular function, greater interocular suppression, and the presence of nystagmus. Fellow-eye deficits were not associated with any of these factors, but a temporo-nasal asymmetry for global motion perception in favor of nasalward motion suggested a general disruption in motion perception. Conclusions: Deficits in motion-defined form perception are common in children with deprivation amblyopia and may reflect a problem in motion processing that relies on binocular mechanisms.
Databáze:	MEDLINE
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