Chronic Migraine May Be Associated With Postprandial Hypoglycemia in Adult Men: A Case Series.

Autor:	Amendolara A; Federated Department of Biology, New Jersey Institute of Technology, Newark, USA.; Department of Biomedical Sciences, Noorda College of Osteopathic Medicine, Provo, USA., Magoffin WD; Department of Biomedical Sciences, Noorda College of Osteopathic Medicine, Provo, USA., Naik AU; Department of Biomedical Sciences, Noorda College of Osteopathic Medicine, Provo, USA., Sant D; Department of Biomedical Sciences, Noorda College of Osteopathic Medicine, Provo, USA., Kriak J; Department of Biomedical Sciences, Noorda College of Osteopathic Medicine, Provo, USA., Green B; Neurology, Migraine and Neurological Rehabilitation Center, Provo, USA., Bills K; Department of Biomedical Sciences, Noorda College of Osteopathic Medicine, Provo, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Feb 26; Vol. 16 (2), pp. e54987. Date of Electronic Publication: 2024 Feb 26 (Print Publication: 2024).
DOI:	10.7759/cureus.54987
Abstrakt:	Migraine is a common neurological disorder that significantly impacts patients around the world. In the United States, one in six individuals suffers from a migraine disorder. Despite its high prevalence, the etiology of migraine is not well understood. Multiple factors likely contribute to the development of both acute and chronic migraine, making the consensus as to the cause and treatment difficult. Presented here are three case studies involving adult males suffering from chronic migraine. Each subject provided a medical history and underwent physical, psychological, and neurological examinations. In addition, relevant bloodwork and cervical spine X-rays were obtained. Physical examination, laboratory studies, imaging, and psychological metrics were unremarkable with the notable exception of the three-hour oral glucose tolerance tests. All three patients displayed hypoglycemia at three hours. Furthermore, their symptoms markedly improved with the initiation of a ketogenic diet. These data are suggestive of a potential link between postprandial hypoglycemia and chronic migraine. Despite the small sample size, we feel that this report presents possible evidence for a connection between postprandial hypoglycemia and chronic migraine. Furthermore, properly controlled studies of larger sample sizes are required, but we suggest that clinicians consider screening patients for this easily overlooked metabolic disturbance, especially in the absence of other options. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Amendolara et al.)
Databáze:	MEDLINE
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