| Autor: |
Preda M; Department of Microbiology, Parasitology and Virology, Faculty of Midwives and Nursing, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.; Clinical Laboratory of Medical Microbiology, Marius Nasta Institute of Pneumology, 050159 Bucharest, Romania., Chivu RD; Department of Public Health and Health Management, Faculty of Midwifery and Nursing, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania., Ditu LM; National Institute for Research & Development in Chemistry and Petrochemistry-ICECHIM Bucharest, 202 Spl. Independentei, 060021 Bucharest, Romania.; Faculty of Biology, University of Bucharest, 90 Panduri Street, 050663 Bucharest, Romania., Popescu O; National Reference Laboratory of Tuberculosis, Marius Nasta Institute of Pneumology, 050159 Bucharest, Romania., Manolescu LSC; Department of Microbiology, Parasitology and Virology, Faculty of Midwives and Nursing, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.; Clinical Laboratory of Medical Microbiology, Marius Nasta Institute of Pneumology, 050159 Bucharest, Romania. |
| Abstrakt: |
Candida auris poses a serious threat to infection control and patient care since it can produce invasive infections that have a high fatality rate, has been linked to outbreaks in hospital environments, and is typically resistant to several antifungal medications. Since its first description in 2009, six clades have been described. The emerging fungal pathogen possesses adhesins that allow it to adhere to host tissues and medical devices, can form biofilms, produces various hydrolytic enzymes, employs several strategies to evade host immune responses, and exhibits high genetic diversity, which may contribute to its ability to adapt to different environmental conditions and evade host defenses. C. auris is very resistant to various disinfectants and may be difficult to detect. |
