Structural insight and in silico prediction of the pharmacokinetic parameters and toxicity of alkaline earth metal compounds strontium and barium with the non-steroidal anti-inflammatory drug nimesulide.

Autor: Rybczyńska M; Faculty of Chemistry, University of Gdansk, W. Stwosza 63, 80-308 Gdansk, Poland. artur.sikorski@ug.edu.pl., Sikorski A; Faculty of Chemistry, University of Gdansk, W. Stwosza 63, 80-308 Gdansk, Poland. artur.sikorski@ug.edu.pl.
Jazyk: angličtina
Zdroj: Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2024 Apr 16; Vol. 53 (15), pp. 6501-6506. Date of Electronic Publication: 2024 Apr 16.
DOI: 10.1039/d4dt00446a
Abstrakt: In the crystals of alkaline earth metal compounds strontium and barium with the non-steroidal anti-inflammatory drug nimesulide, the strontium cation is nine-coordinated with a distorted tricapped trigonal prismatic geometry TCTPR-9, whereas the ten-coordinated barium ion exhibits a distorted tetracapped trigonal prismatic geometry TCTPR-10.
Databáze: MEDLINE