Evaluation of different substance combinations in a multiple-session mesotherapy protocol for the management of osteoarthritis in dogs: a retrospective study.
| Autor: | Alves JC; 1Divisão de Medicina Veterinária, Guarda Nacional Republicana, Lisbon, Portugal.; 2Faculty of Veterinary Medicine, Lusófona University, Lisbon, Portugal.; 3Centro de Ciência Animal e Veterinária, Lusófona University, Lisbon, Portugal.; 4Mediterranean Institute for Agriculture, Environment and Development, Instituto de Investigação e Formação Avançada, Universidade de Évora, Évora, Portugal., Santos A; 1Divisão de Medicina Veterinária, Guarda Nacional Republicana, Lisbon, Portugal., Lafuente P; 5Universidad Internacional de La Rioja, Logroño, Spain. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 2024 Mar 19; Vol. 262 (8), pp. 1-7. Date of Electronic Publication: 2024 Mar 19 (Print Publication: 2024). |
| DOI: | 10.2460/javma.23.10.0588 |
| Abstrakt: | Objective: To describe the effect of different substance combinations administered through mesotherapy in dogs with hip osteoarthritis. Animals: 104 dogs. Methods: In this retrospective study, 4 groups (dogs treated with a combination of lidocaine, piroxicam, and thiocolchicoside [MG]; dogs treated with lidocaine, piroxicam, and Traumeel [TG]; dogs treated with lidocaine, piroxicam, and glucosamine [GG]; and dogs treated with the same combination as in MG combined with a photobiomodulation session [MPG]) were set. For all groups, the same treatment frequency was followed. Response to treatment was measured with the Canine Brief Pain Inventory (divided into pain interference score and pain severity score), Liverpool Osteoarthritis in Dogs (LOAD), and Canine Orthopedic Index (divided into function, gait, stiffness, and quality of life) before treatment and 15, 30, 60, 90, and 120 days after treatment. Cox proportional hazard regression analysis was used to investigate the influence of treatment, age, sex, body weight, breed, and Orthopedic Foundation for Animals score. Results: Dogs had a mean age of 7.6 ± 3.1 years and body weight of 28.6 ± 5.5 kg. Hip osteoarthritis was classified as mild (4), moderate (70), or severe (30). Greater improvements were observed in MG and MPG. Kaplan-Meier estimators showed MG and MPG had longer periods with clinically significant results. Treatment was the covariable that contributed more frequently to the outcomes observed. Clinical Relevance: The combination used in MG, particularly combined with photobiomodulation, produced longer-lasting clinically significant results. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|