| Autor: |
Virina N; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Kesova E; 2I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Moscow, Russia., Gadzhieva D; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., August Y; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Khokhlov P; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Komissarova N; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Kinder D; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Khakhaev I; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Ishkova S; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Zelenina V; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Taimazova A; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Trofimova A; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia., Kachanov D; 1NWSMU named after I.I. Mechnikov of the Ministry of Health of Russia, Russia, St. Petersburg, Russia. |
| Abstrakt: |
At the current stage of healthcare development, the inclusion of immunomodulators in the complex pharmacotherapy of various immunoinflammatory and viral diseases is widely discussed, but due to the lack of sufficient research and a broad evidence base, not all drugs with similar properties are used in medicine. According to the information obtained from the instructions for the use of immunomodulators, it was obtained that the main contraindications to their use include the prescription of children, pregnant women, and women during breastfeeding. In this study, we evaluated the effects of immunomodulatory drugs: aminodihydrophthalazindione sodium and meglumine acridonacetate, on the early developmental stages of Danio rerio (Zebrafish) embryos. |
