Evidence-Based Guideline for the management of osteoporosis in men.

Autor: Fuggle NR; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK., Beaudart C; Clinical Pharmacology and Toxicology Research Unit, Faculty of Medicine, NARILIS, University of Namur, Namur, Belgium.; WHO Collaborating Centre for Epidemiology of Musculoskeletal Health and Ageing, Liège, Belgium., Bruyère O; WHO Collaborating Centre for Epidemiology of Musculoskeletal Health and Ageing, Liège, Belgium., Abrahamsen B; Odense Patient Data Explorative Network, Institute of Clinical Research University of Southern Denmark, Odense, Denmark., Al-Daghri N; Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia., Burlet N; WHO Collaborating Centre for Epidemiology of Musculoskeletal Health and Ageing, Liège, Belgium.; The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), Liege, Belgium., Chandran M; Osteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital, DUKE NUS Medical School, Singapore, Singapore., Rosa MM; Laboratory of Clinical and Therapeutical Pharmacology, University of Lisbon, Lisbon, Portugal., Cortet B; Department of Rheumatology, University of Lille, Lille, France., Demonceau C; WHO Collaborating Centre for Epidemiology of Musculoskeletal Health and Ageing, Liège, Belgium., Dere W; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA., Halbout P; The International Osteoporosis Foundation (IOF), Nyon, Switzerland., Hiligsmann M; Department of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands., Kanis JA; Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, UK.; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Australia., Kaufman JM; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium., Kurth A; Department of Orthopaedic and Trauma Surgery, Community Clinics Middle Rhine, Campus Kemperhof, Koblenz, Germany., Lamy O; Centre interdisciplinaire des maladies osseuses, Département de l'appareil locomoteur, Centre hospitalier universitaire vaudois, Lausanne, Switzerland., Laslop A; Scientific Office, Federal Office for Safety in Health Care, Vienna, Austria., Maggi S; CNR Aging Branch-IN, Padua, Italy., Matijevic R; University of Novi Sad, Faculty of Medicine, Clinic for Orthopedic Surgery and Traumatology, Clinical Center of Vojvodina, Novi Sad, Serbia., McCloskey E; Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, UK., Mobasheri A; Research Unit of Medical Imaging, Physics, and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland., Prieto Yerro MC; Agencia Española de Medicamentos y Productos Sanitarios, Madrid, Spain., Radermecker RP; Department of Diabetes, Nutrition and Metabolic disorders, Clinical pharmacology, University of Liège, CHU de Liège, Liège, Belgium., Sabico S; Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia., Al-Saleh Y; Odense Patient Data Explorative Network, Institute of Clinical Research University of Southern Denmark, Odense, Denmark.; Department of Endocrinology, Dr. Mohammad Alfagih Hospital, Riyadh, Saudi Arabia., Silverman S; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Veronese N; Department of Internal Medicine, Geriatrics Section, University of Palermo, Palermo, Italy., Rizzoli R; Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland., Cooper C; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.; NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Reginster JY; WHO Collaborating Centre for Epidemiology of Musculoskeletal Health and Ageing, Liège, Belgium.; Protein Research Chair, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia., Harvey NC; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK. nch@mrc.soton.ac.uk.; NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK. nch@mrc.soton.ac.uk.
Jazyk: angličtina
Zdroj: Nature reviews. Rheumatology [Nat Rev Rheumatol] 2024 Apr; Vol. 20 (4), pp. 241-251. Date of Electronic Publication: 2024 Mar 14.
DOI: 10.1038/s41584-024-01094-9
Abstrakt: Historically, osteoporosis has been viewed as a disease of women, with research, trials of interventions and guidelines predominantly focused as such. It is apparent, however, that this condition causes a substantial health burden in men also, and that its assessment and management must ultimately be addressed across both sexes. In this article, an international multidisciplinary working group of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases presents GRADE-assessed recommendations for the diagnosis, monitoring and treatment of osteoporosis in men. The recommendations are based on a comprehensive review of the latest research related to diagnostic and screening approaches for osteoporosis and its associated high fracture risk in men, covering disease burden, appropriate interpretation of bone densitometry (including the use of a female reference database for densitometric diagnosis in men) and absolute fracture risk, thresholds for treatment, and interventions that can be used therapeutically and their health economic evaluation. Future work should specifically address the efficacy of anti-osteoporosis medications, including denosumab and bone-forming therapies.
(© 2024. Springer Nature Limited.)
Databáze: MEDLINE
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