Dermatoscopic patterns of cutaneous metastases: A multicentre cross-sectional study of the International Dermoscopy Society.

Autor: Tiodorovic D; Clinic of Dermatovenerology, University Clinical Center of Nis, Medical Faculty, University of Nis, Nis, Serbia., Stojkovic-Filipovic J; Clinic of Dermatology and Venereology, University Clinical Center of Serbia, Faculty of Medicine, Department of Dermatology and Venereology, University of Belgrade, Belgrade, Serbia., Marghoob A; Memorial Sloan Kettering Cancer Center, Uniondale, New York, USA., Argenziano G; Dermatology Unit, University of Campania, Naples, Italy., Puig S; Dermatology Department, Hospital Clinic Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain., Malvehy J; Dermatology Department, Hospital Clinic Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain., Tognetti L; Dermatology Unit, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy., Pietro R; Dermatology Unit, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy., Akay BN; Medicine Faculty Department of Dermatology, Ankara University, Ankara, Turkey., Zalaudek I; Department of Dermatology and Venerology, Medical University of Trieste, Trieste, Italy., Haenssle HA; Department of Dermatology, University of Heidelberg, Heidelberg, Germany., Müller-Christmann C; Department of Dermatology, University of Heidelberg, Heidelberg, Germany., Cinotti E; Dermatology Unit, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy., Perrot JL; Department of Dermatology, CHU Saint Etienne, Saint-Etienne, France., Zaballos P; Dermatology Department, Hospital de Sant Pau i Santa Tecla, Tarragota, Spain., Bakos RM; Department of Dermatology, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul-Porto Alegre, Porto Alegre, Brazil., Thomas L; Department of Dermatology, Centre Hospitalier Lyon Sud, Lyons Cancer Research Center, Lyon 1 University, Lyon, France., Peris K; Dermatologia, Dipartimento di Medicina e Chirurgia Traslazionale, UOC di Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy., Lallas A; First Department of Dermatology, School of Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece., Apalla Z; First Department of Dermatology, School of Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece., Kreusch JF; Private Dermatological Practice, Luebeck, Germany., Tromme I; Department of Dermatology and Melanoma Clinic St Luc Hospital, Catholic, University of Louvain, Brussels, Belgium., Stratigos AJ; Andreas Sygros Hospital for Cutaneous and Venereal Diseases, Athens, Greece., Pizzichetta MA; Department of Dermatology, University of Trieste, Aviano, Italy.; Department of Medical Oncology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy., Kandolf L; Department of Dermatology and Venereology, Faculty of Medicine, Military Medical Academy, Belgrade, Serbia., Longo C; Department of Dermatology, University of Modena and Reggio Emili, Modena, Italy.; Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Skin Cancer Center, Reggio Emilia, Italy., Blum A; Public, Private and Teaching Practice of Dermatology, Konstanz, Germany., Tanaka M; Department of Dermatology, Tokyo Women's Medical University Adachi Medical Center, Tokyo, Japan., Hofmann-Wellenhof R; Department of Dermatology and Venerology, Medical University Graz, Graz, Austria., Jovic A; Clinic of Dermatovenerology, University Clinical Center of Nis, Nis, Serbia., Paoli J; Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy, Region Västra Götaland, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden., Buljan M; Department of Dermatology and Venereology, Sestre Milosrdnice University Hospital Centre, School of Dental Medicine, University of Zagreb, Zagreb, Croatia., Espasandín-Arias M; Department of Dermatology, University Hospital of Pontevedra, Pontevedra, Spain., Cabo H; University of Buenos Aires, Buenos Aires, Argentina., Saa SR; Department of Dermatology, Hospital Del Carmen, Mendoza, Argentina., Salerni G; Department of Dermatology, Hospital Provincial del Centenario, National University of Rosario, Rosario, Argentina., Nazzaro G; Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Kaminska-Winciorek G; Department of Bone Marrow Transplantation and Hematology-Oncology; Skin Cancer and Melanoma Team, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland., Damiani G; Italian Center of Precisione Medicine and Chronic Inflammation Milan, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy., Geszti F; Smartderm Medical Office, Budapest, Hungary., Kittler H; Department of Dermatology, Medical University of Vienna, Vienna, Austria.
Jazyk: angličtina
Zdroj: Journal of the European Academy of Dermatology and Venereology : JEADV [J Eur Acad Dermatol Venereol] 2024 Jul; Vol. 38 (7), pp. 1432-1438. Date of Electronic Publication: 2024 Mar 14.
DOI: 10.1111/jdv.19962
Abstrakt: Background: The detection of cutaneous metastases (CMs) from various primary tumours represents a diagnostic challenge.
Objectives: Our aim was to evaluate the general characteristics and dermatoscopic features of CMs from different primary tumours.
Methods: Retrospective, multicentre, descriptive, cross-sectional study of biopsy-proven CMs.
Results: We included 583 patients (247 females, median age: 64 years, 25%-75% percentiles: 54-74 years) with 632 CMs, of which 52.2% (n = 330) were local, and 26.7% (n = 169) were distant. The most common primary tumours were melanomas (n = 474) and breast cancer (n = 59). Most non-melanoma CMs were non-pigmented (n = 151, 95.6%). Of 169 distant metastases, 54 (32.0%) appeared on the head and neck region. On dermatoscopy, pigmented melanoma metastases were frequently structureless blue (63.6%, n = 201), while amelanotic metastases were typified by linear serpentine vessels and a white structureless pattern. No significant difference was found between amelanotic melanoma metastases and CMs of other primary tumours.
Conclusions: The head and neck area is a common site for distant CMs. Our study confirms that most pigmented melanoma metastasis are structureless blue on dermatoscopy and may mimic blue nevi. Amelanotic metastases are typified by linear serpentine vessels and a white structureless pattern, regardless of the primary tumour.
(© 2024 European Academy of Dermatology and Venereology.)
Databáze: MEDLINE
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