Case Report: Clinical and Pathological Findings of Tuberculous Gumma: A Case Report and Literature Review.

Autor:	Deng LJ; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Ye Q; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Dermatology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China., Luo SY, Wang QX; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Fang S; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jazyk:	angličtina
Zdroj:	The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2024 Mar 12; Vol. 110 (4), pp. 805-808. Date of Electronic Publication: 2024 Mar 12 (Print Publication: 2024).
DOI:	10.4269/ajtmh.23-0510
Abstrakt:	Tuberculous gumma (TG) is a rare type of cutaneous tuberculosis thought to occur as a result of the hematogenous spread of Mycobacterium tuberculosis, which is more common in immunosuppressed individuals. An 8-year-old boy presented with a 2-month history of multiple indolent enlarging ulcerated nodules on his left upper extremity. He had a past medical history of bacille Calmette-Guerin vaccine induced lupus vulgaris. Skin biopsy of the nodules showed granulomas and neutrophil-dominated purulent inflammation. Ziehl-Neelsen staining was negative, and the cultures were positive for M. tuberculosis. Furthermore, the M. tuberculosis complex was identified using metagenomic next-generation sequencing. Standard antitubercular therapy was started at full doses, and the skin lesions had significantly improved 3 months later. Here we review the literature since 2000 and describe the clinical and pathological features of TG.
Databáze:	MEDLINE
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