Nano-therapeutics: The upcoming nanomedicine to treat cancer.

Autor: Khan H; Department of Biochemistry, Jawahar Lal Nehru Medical College, Aligarh Muslim University, Aligarh, India., Shahab U; Department of Biochemistry, King George Medical University, Lucknow, India., Alshammari A; Department of Internal Medicine, College of Medicine, University of Hail, Ha'il, Saudi Arabia., Alyahyawi AR; Department of Diagnostic Radiology, College of Applied Medical Science, University of Hail, Ha'il, Saudi Arabia.; Centre for Nuclear and Radiation Physics, Department of Physics, University of Surrey, Guildford, UK., Akasha R; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Ha'il, Saudi Arabia., Alharazi T; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Ha'il, Saudi Arabia., Ahmad R; Department of Biochemistry, Jawahar Lal Nehru Medical College, Aligarh Muslim University, Aligarh, India., Khanam A; Department of Biotechnology & Life Science, Institute of Biomedical Education & Research, Mangalayatan University, Aligarh, India., Habib S; Department of Biochemistry, Jawahar Lal Nehru Medical College, Aligarh Muslim University, Aligarh, India., Kaur K; University Centre for Research and Development, Chandigarh University, Mohali, India., Ahmad S; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Ha'il, Saudi Arabia., Moinuddin; Department of Biochemistry, Jawahar Lal Nehru Medical College, Aligarh Muslim University, Aligarh, India.
Jazyk: angličtina
Zdroj: IUBMB life [IUBMB Life] 2024 Aug; Vol. 76 (8), pp. 468-484. Date of Electronic Publication: 2024 Mar 05.
DOI: 10.1002/iub.2814
Abstrakt: Nanotechnology is considered a successful approach for cancer diagnosis and treatment. Preferentially, cancer cell recognition and drug targeting via nano-delivery system include the penetration of anticancer agents into the cell membrane to damage the cancer cell by protein modification, DNA oxidation, or mitochondrial dysfunction. The past research on nano-delivery systems and their target has proven the beneficial achievement in a malignant tumor. Modern perceptions using inventive nanomaterials for cancer management have been offered by a multifunctional platform based on various nano-carriers with the probability of imaging and cancer therapy simultaneously. Emerging nano-delivery systems in cancer therapy still lack knowledge of the biological functions behind the interaction between nanoparticles and cancer cells. Since the potential of engineered nanoparticles addresses the various challenges, limiting the success of cancer therapy subsequently, it is a must to review the molecular targeting of a nano-delivery system to enhance the therapeutic efficacy of cancer. This review focuses on using a nano-delivery system, an imaging system, and encapsulated nanoparticles for cancer therapy.
(© 2024 International Union of Biochemistry and Molecular Biology.)
Databáze: MEDLINE
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