Transboundary determinants of avian zoonotic infectious diseases: challenges for strengthening research capacity and connecting surveillance networks.

Autor:	Fair JM; Genomics and Bioanalytics, Los Alamos National Laboratory, Los Alamos, NM, United States., Al-Hmoud N; Bio-Safety and Bio-Security Center, Royal Scientific Society, Amman, Jordan., Alrwashdeh M; Bio-Safety and Bio-Security Center, Royal Scientific Society, Amman, Jordan., Bartlow AW; Genomics and Bioanalytics, Los Alamos National Laboratory, Los Alamos, NM, United States., Balkhamishvili S; Center of Wildlife Disease Ecology, Ilia State University, Tbilisi, Georgia., Daraselia I; Center of Wildlife Disease Ecology, Ilia State University, Tbilisi, Georgia., Elshoff A; CRDF Global, Arlington, VA, United States., Fakhouri L; CRDF Global, Arlington, VA, United States., Javakhishvili Z; Center of Wildlife Disease Ecology, Ilia State University, Tbilisi, Georgia., Khoury F; Department of Biology and Biotechnology, American University of Madaba, Madaba, Jordan., Muzyka D; National Scientific Center, Institute of Experimental and Clinical Veterinary Medicine, Kharkiv, Ukraine., Ninua L; CRDF Global, Arlington, VA, United States., Tsao J; Department of Fisheries and Wildlife, Michigan State University, East Lansing, MI, United States., Urushadze L; National Center for Disease Control and Public Health (NCDC) of Georgia, Tbilisi, Georgia., Owen J; Department of Fisheries and Wildlife, Michigan State University, East Lansing, MI, United States.
Jazyk:	angličtina
Zdroj:	Frontiers in microbiology [Front Microbiol] 2024 Feb 16; Vol. 15, pp. 1341842. Date of Electronic Publication: 2024 Feb 16 (Print Publication: 2024).
DOI:	10.3389/fmicb.2024.1341842
Abstrakt:	As the climate changes, global systems have become increasingly unstable and unpredictable. This is particularly true for many disease systems, including subtypes of highly pathogenic avian influenzas (HPAIs) that are circulating the world. Ecological patterns once thought stable are changing, bringing new populations and organisms into contact with one another. Wild birds continue to be hosts and reservoirs for numerous zoonotic pathogens, and strains of HPAI and other pathogens have been introduced into new regions via migrating birds and transboundary trade of wild birds. With these expanding environmental changes, it is even more crucial that regions or counties that previously did not have surveillance programs develop the appropriate skills to sample wild birds and add to the understanding of pathogens in migratory and breeding birds through research. For example, little is known about wild bird infectious diseases and migration along the Mediterranean and Black Sea Flyway (MBSF), which connects Europe, Asia, and Africa. Focusing on avian influenza and the microbiome in migratory wild birds along the MBSF, this project seeks to understand the determinants of transboundary disease propagation and coinfection in regions that are connected by this flyway. Through the creation of a threat reduction network for avian diseases (Avian Zoonotic Disease Network, AZDN) in three countries along the MBSF (Georgia, Ukraine, and Jordan), this project is strengthening capacities for disease diagnostics; microbiomes; ecoimmunology; field biosafety; proper wildlife capture and handling; experimental design; statistical analysis; and vector sampling and biology. Here, we cover what is required to build a wild bird infectious disease research and surveillance program, which includes learning skills in proper bird capture and handling; biosafety and biosecurity; permits; next generation sequencing; leading-edge bioinformatics and statistical analyses; and vector and environmental sampling. Creating connected networks for avian influenzas and other pathogen surveillance will increase coordination and strengthen biosurveillance globally in wild birds. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Fair, Al-Hmoud, Alrwashdeh, Bartlow, Balkhamishvili, Daraselia, Elshoff, Fakhouri, Javakhishvili, Khoury, Muzyka, Ninua, Tsao, Urushadze and Owen.)
Databáze:	MEDLINE
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