Diagnostic performance of blue laser imaging for early detection of gastric cancer: A systematic review and meta-analysis.

Autor: Shaik MR; Department of Medicine, University of Maryland Medical Center Midtown Campus, 827 Linden Ave, Baltimore, MD, 21201, USA. shaikrifat13@gmail.com., Canakis A; Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD, USA., Shaik NA; Department of Medicine, University of Maryland Medical Center Midtown Campus, 827 Linden Ave, Baltimore, MD, 21201, USA., Bomman S; Division of Gastroenterology and Hepatology, University of Arizona School of Medicine, Tucson, AZ, USA., Dahiya DS; Division of Gastroenterology and Hepatology, The University of Kansas School of Medicine, Kansas City, USA., Gorman E; Health Sciences and Human Services Library, University of Maryland, Baltimore, MD, USA., Bilal M; Division of Gastroenterology, University of Minnesota and Minneapolis VA Health Care System, Minneapolis, MN, USA., Chandan S; Division of Gastroenterology, Creighton University School of Medicine, Omaha, NE, USA.
Jazyk: angličtina
Zdroj: Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology [Indian J Gastroenterol] 2024 Oct; Vol. 43 (5), pp. 976-985. Date of Electronic Publication: 2024 Feb 28.
DOI: 10.1007/s12664-023-01495-w
Abstrakt: Background: Gastric cancer (GC) is associated with a significant global health burden and high mortality rates when diagnosed at later stages. The diagnosis often occurs at advanced stages when treatment options are limited and less effective. Early detection strategies are crucial to improving survival rates and outcomes for patients. Blue laser imaging (BLI) is an image-enhanced endoscopy technique that utilizes white light and narrow-band light to detect pathological changes in the mucosal architecture. This study aims at investigating the diagnostic performance of BLI for the detection of GC.
Methods: A comprehensive search was conducted across multiple databases from inception until March 2023. Studies assessing the diagnostic efficacy of BLI for GC detection were included. The sensitivity, specificity and accuracy of BLI were calculated using pooled proportions and 95% confidence intervals (CI) with a random-effects model. Heterogeneity among the included studies was assessed using the I 2 statistic.
Results: Six studies were included in the pooled analysis. There were 708 patients with 380 GC lesions. Most of the lesions involved the lower two-thirds of the stomach. The pooled performance metrics of BLI for GC detection were as follows: sensitivity of 91.9% (95% CI 83.3-96.3%; I 2 = 82.3%), specificity of 93.4% (95% CI 82.0-97.8%; I 2 = 87.9%) and accuracy of 95.4% (95% CI 72.6-99.8%; I 2 = 73.6%).
Conclusion: BLI demonstrates high diagnostic efficacy for the detection of GC. BLI can be a valuable tool in clinical practice. However, large-scale, randomized controlled studies are needed to further establish the role of BLI in routine clinical practice for GC detection.
(© 2024. Indian Society of Gastroenterology.)
Databáze: MEDLINE
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