Advances in Nanomaterials and Composites Based on Mesoporous Materials as Antimicrobial Agents: Relevant Applications in Human Health.

Autor: Gomez GE; Instituto de Investigaciones en Tecnología Química (INTEQUI), Departamento de Química, Universidad Nacional de San Luis (UNSL), CONICET, Ejército de los Andes 950, San Luis D5700BWS, Argentina., Hamer M; Instituto de Ciencias, Universidad Nacional de General Sarmiento-CONICET, Juan María Gutiérrez 1150, Los Polvorines CP1613, Argentina., Regiart MD; Instituto de Química San Luis (INQUISAL), Departamento de Química, Universidad Nacional de San Luis (UNSL), CONICET, Chacabuco 917, San Luis D5700BWS, Argentina., Tortella GR; Centro de Excelencia en Investigación Biotecnológica Aplicada al Medio Ambiente (CIBAMA), Facultad de Ingeniería y Ciencias, Universidad de La Frontera, Av. Francisco Salazar 01145, Temuco 4811230, Chile.; Departamento de Ingeniería Química, Facultad de Ingeniería y Ciencias, Universidad de La Frontera, Av. Francisco Salazar 01145, Temuco 4811230, Chile., Seabra AB; Center for Natural and Human Sciences, Federal University of ABC (UFABC), Avenida dos Estados, Saint Andrew 09210-580, Brazil., Soler Illia GJAA; Instituto de Nanosistemas, Escuela de Bio y Nanotecnología, Universidad Nacional de General San Martín-CONICET, Av. 25 de mayo 1169, San Martín B1650KNA, Argentina., Fernández-Baldo MA; Instituto de Química San Luis (INQUISAL), Departamento de Química, Universidad Nacional de San Luis (UNSL), CONICET, Chacabuco 917, San Luis D5700BWS, Argentina.
Jazyk: angličtina
Zdroj: Antibiotics (Basel, Switzerland) [Antibiotics (Basel)] 2024 Feb 09; Vol. 13 (2). Date of Electronic Publication: 2024 Feb 09.
DOI: 10.3390/antibiotics13020173
Abstrakt: Nanotechnology has emerged as a cornerstone in contemporary research, marked by the advent of advanced technologies aimed at nanoengineering materials with diverse applications, particularly to address challenges in human health. Among these challenges, antimicrobial resistance (AMR) has risen as a significant and pressing threat to public health, creating obstacles in preventing and treating persistent diseases. Despite efforts in recent decades to combat AMR, global trends indicate an ongoing and concerning increase in AMR. The primary contributors to the escalation of AMR are the misuse and overuse of various antimicrobial agents in healthcare settings. This has led to severe consequences not only in terms of compromised treatment outcomes but also in terms of substantial financial burdens. The economic impact of AMR is reflected in skyrocketing healthcare costs attributed to heightened hospital admissions and increased drug usage. To address this critical issue, it is imperative to implement effective strategies for antimicrobial therapies. This comprehensive review will explore the latest scientific breakthroughs within the metal-organic frameworks and the use of mesoporous metallic oxide derivates as antimicrobial agents. We will explore their biomedical applications in human health, shedding light on promising avenues for combating AMR. Finally, we will conclude the current state of research and offer perspectives on the future development of these nanomaterials in the ongoing battle against AMR.
Databáze: MEDLINE