Symptomatic and functional recovery after transurethral resection of bladder tumor: Data from ecological momentary symptom assessment.

Autor: Strother M; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA. Electronic address: m12912988@gmail.com., Barlotta R; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Uzzo R; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Bloom E; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Jazayeri SB; Department of Urology, University of Florida Jacksonville, Jacksonville, FL., Bigalli AC; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Schober J; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Lee J; Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Bernstein A; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Ginsburg K; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Handorf E; Department of Biostatistics and Bioinformatics, Fox Chase Cancer Center, Philadelphia, PA., Chen DY; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Correa A; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Greenberg R; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Smaldone M; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Viterbo R; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA., Kutikov A; Department of Urology, Fox Chase Cancer Center, Philadelphia, PA.
Jazyk: angličtina
Zdroj: Urologic oncology [Urol Oncol] 2024 Apr; Vol. 42 (4), pp. 117.e1-117.e10. Date of Electronic Publication: 2024 Feb 17.
DOI: 10.1016/j.urolonc.2023.12.007
Abstrakt: Objectives: To quantitatively describe the nature, severity, and duration of symptoms and functional impairment during recovery from transurethral resection of bladder tumors.
Materials and Methods: All patients scheduled for transurethral resection were approached for enrollment in a text-message based ecological momentary symptom assessment platform. Nine patients reported outcomes were measured 7 days before surgery and on postoperative days 1, 2, 3, 5, 7, 10, and 14 using a 5-point Likert scale. Self-reported degree of hematuria was collected using a visual scale. Clinical data was collected via retrospective chart review.
Results: A total of 159 patients were analyzed. Postoperative symptoms were overall mild, with the largest differences from baseline to postoperative day 1 seen in dysuria (median 0/5 vs. 3/5) and ability to work (median 5/5 vs. 4/5). Recovery was generally rapid, with 76% of patients reporting ≥4/5 agreement with the statement "I feel recovered from surgery" by postoperative day 2, although 15% of patients reported persistently lower levels of agreement on postoperative day 10 or 14. Patients undergoing larger resections (≥2cm) did take longer to return to baseline in multiple symptom domains, but the difference of medians vs. those undergoing smaller resections was less than 1 day across all domains. Multivariable analysis suggested that receiving perioperative intravesical chemotherapy was associated with longer time to recovery. 84% of patients reported clear yellow urine by postoperative day 3.
Conclusion: In this population, hematuria and negative effects on quality of life resulting from transurethral resection of bladder tumors were generally mild and short-lived, although a small number of patients experienced longer recoveries.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Dr. Jazayeri is the Chief Executive Office of Medaux Incorporated.
(Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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