How does COVID-19 vaccination affect long-COVID symptoms?

Autor: Asadi-Pooya AA; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Neurology, Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, PA, United States of America., Nemati M; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Shahisavandi M; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Nemati H; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Karimi A; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Jafari A; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Nasiri S; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Mohammadi SS; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Rahimian Z; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Bayat H; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Akbari A; Department of Anesthesiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Emami A; Burn & Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Eilami O; HIV and AIDS Research Center, Department of Infectious Disease and Family Medicine, Shiraz University of Medical Science, Shiraz, Iran.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2024 Feb 07; Vol. 19 (2), pp. e0296680. Date of Electronic Publication: 2024 Feb 07 (Print Publication: 2024).
DOI: 10.1371/journal.pone.0296680
Abstrakt: Objective: The current study aimed to identify the association between COVID-19 vaccination and prolonged post-COVID symptoms (long-COVID) in adults who reported suffering from this condition.
Methods: This was a retrospective follow-up study of adults with long-COVID syndrome. The data were collected during a phone call to the participants in January-February 2022. We inquired about their current health status and also their vaccination status if they agreed to participate.
Results: In total, 1236 people were studied; 543 individuals reported suffering from long long- COVID (43.9%). Chi square test showed that 15 out of 51 people (29.4%) with no vaccination and 528 out of 1185 participants (44.6%) who received at least one dose of any vaccine had long long- COVID symptoms (p = 0.032).
Conclusions: In people who have already contracted COVID-19 and now suffer from long-COVID, receiving a COVID vaccination has a significant association with prolonged symptoms of long-COVID for more than one year after the initial infection. However, vaccines reduce the risk of severe COVID-19 (including reinfections) and its catastrophic consequences (e.g., death). Therefore, it is strongly recommended that all people, even those with a history of COVID-19, receive vaccines to protect themselves against this fatal viral infection.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Asadi-Pooya et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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