Accelerating Healing and Relieving Pain: High-Intensity Laser Therapy for Paraneoplastic Cutaneous Vasculitis Associated with Multiple Myeloma.

Autor: Felipe Fernandes Maciel K; Medical School, Brasília University - Campus Darcy Ribeiro, Brasília, DF, Brazil., Cordeiro AH; Department of Vascular Surgery, Brasília Institute of Angiology, Brasília, DF, Brazil., Fernandes Batista de Amorim R; Medical School, Brasília University - Campus Darcy Ribeiro, Brasília, DF, Brazil., Bertti Coelho L; Department of Vascular Surgery, Brasília Institute of Angiology, Brasília, DF, Brazil., de Freitas Cordeiro M; Education and Health Sciences Faculty, Brasilia Unified Learning Center - CEUB, Brasília, DF, Brazil., Pinto TDA; Medical School, Brasília University - Campus Darcy Ribeiro, Brasília, DF, Brazil.
Jazyk: angličtina
Zdroj: The American journal of case reports [Am J Case Rep] 2024 Feb 07; Vol. 25, pp. e942322. Date of Electronic Publication: 2024 Feb 07.
DOI: 10.12659/AJCR.942322
Abstrakt: BACKGROUND Leukocytoclastic vasculitis (LCV) is an atypical form of cutaneous paraneoplastic manifestation. Its association with multiple myeloma (MM) is even rarer and is associated with poor prognosis and short survival, regardless of the therapy instituted. Different treatment approaches are necessary. We present a case in which LCV was the first manifestation of MM, and high-intensity laser therapy (HILT) was used as an option to accelerate healing and control pain. CASE REPORT A 76-year-old woman presented with pain and paresthesia in her lower limbs, associated with palpable purpura. The clinical diagnosis was small-vessel vasculitis. Laboratory tests showed an elevated gamma globulin monoclonal peak on protein electrophoresis. The immunophenotypic study of bone marrow aspirates led to the diagnosis of MM. Due to pain refractory to conventional analgesics, and the progressive evolution of the lesions, despite corticosteroid therapy, we performed photo-biomodulation with a neodymium-doped yttrium aluminum garnet laser (Nd: YAG), wavelength 1064 nanometers, using a 7-mm probe and energy density 6 J/cm². After the first session, the patient was referred for pain management, and after 5 weeks, we observed complete healing in ulcerated lesions and involution of bullous lesions. CONCLUSIONS This case report shows the positive effects of the Nd: YAG laser in modulating healing and reducing pain. HILT is an innovative, non-invasive, and effective treatment and should be considered a promising technique to accelerate healing and controlling pain.
Databáze: MEDLINE