Pyrantel resistance in canine hookworms in Queensland, Australia.

Autor: Dale A; The University of Queensland, School of Veterinary Science, Gatton, QLD 4343, Australia., Xu G; The University of Queensland, School of Veterinary Science, Gatton, QLD 4343, Australia., Kopp SR; The University of Queensland, School of Veterinary Science, Gatton, QLD 4343, Australia., Jones MK; The University of Queensland, School of Veterinary Science, Gatton, QLD 4343, Australia., Kotze AC; CSIRO Agriculture and Food, Queensland Bioscience Precinct, St. Lucia, Brisbane, QLD 4067, Australia., Abdullah S; The University of Queensland, School of Veterinary Science, Gatton, QLD 4343, Australia. Electronic address: swaid.abdullah@uq.edu.au.
Jazyk: angličtina
Zdroj: Veterinary parasitology, regional studies and reports [Vet Parasitol Reg Stud Reports] 2024 Feb; Vol. 48, pp. 100985. Date of Electronic Publication: 2024 Jan 10.
DOI: 10.1016/j.vprsr.2024.100985
Abstrakt: Hookworms are the most common intestinal nematode parasites of dogs in Australia. The control of these parasites relies mostly on regular deworming with anthelmintics, with pyrantel-based dewormers being a relatively low cost and readily-available option for dog owners. Pyrantel resistance in canine hookworms in Australia was first reported in 2007, however pyrantel-based dewormers are still used against hookworm infection in dogs across Australia. The present study was conducted to evaluate the efficacy of pyrantel against hookworms infecting dogs housed in a shelter facility in Southeast Queensland which receives rescued or surrendered animals from greyhound rescue centres and dog shelters across this region. A total of 10 dogs were examined using the faecal egg count reduction test (FECRT). There was no reduction in FEC in any of the dogs following pyrantel treatment, with drug efficacies ranging from -0.9% to -283.3%. Given that these dogs originated from various sites across Southeast Queensland, the present study suggests that pyrantel resistance is widespread in this region, and hence this anthelmintic may not be a useful option for treatment of hookworm infections in dogs.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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