Infant hedonic/anhedonic processing index (HAPI-Infant): Assessing infant anhedonia and its prospective association with adolescent depressive symptoms.

Autor: Irwin JL; Department of Psychology, Chapman University, Orange, CA, United States of America., Davis EP; Department of Psychology, University of Denver, Denver, CO, United States of America; Department of Pediatrics, University of California, Irvine, CA, United States of America., Sandman CA; Department of Psychiatry and Human Behavior, University of California, Irvine, CA, United States of America., Baram TZ; Department of Pediatrics, University of California, Irvine, CA, United States of America; Department of Anatomy/Neurobiology, University of California, Irvine, CA, United States of America; Department of Neurology, University of California, Irvine, CA, United States of America., Stern HS; Department of Statistics, University of California, Irvine, CA, United States of America., Glynn LM; Department of Psychology, Chapman University, Orange, CA, United States of America. Electronic address: lglynn@chapman.edu.
Jazyk: angličtina
Zdroj: Journal of affective disorders [J Affect Disord] 2024 May 01; Vol. 352, pp. 281-287. Date of Electronic Publication: 2024 Feb 01.
DOI: 10.1016/j.jad.2024.01.225
Abstrakt: Background: Anhedonia, an impairment in the motivation for or experience of pleasure, is a well-established transdiagnostic harbinger and core symptom of mental illness. Given increasing recognition of early life origins of mental illness, we posit that anhedonia should, and could, be recognized earlier if appropriate tools were available. However, reliable diagnostic instruments prior to childhood do not currently exist.
Methods: We developed an assessment instrument for anhedonia/reward processing in infancy, the Infant Hedonic/Anhedonic Processing Index (HAPI-Infant). Exploratory factor and psychometric analyses were conducted using data from 6- and 12-month-old infants from two cohorts (N = 188, N = 212). Then, associations were assessed between infant anhedonia and adolescent self-report of depressive symptoms.
Results: The HAPI-Infant (47-items), exhibited excellent psychometric properties. Higher anhedonia scores at 6 (r = 0.23, p < .01) and 12 months (r = 0.19, p < .05) predicted elevated adolescent depressive symptoms, and these associations were stronger than for established infant risk indicators such as negative affectivity. Subsequent analyses supported the validity of short (27-item) and very short (12-item) versions of this measure.
Limitations: The primary limitations of this study are that the HAPI-Infant awaits additional tests of generalizability and of its ability to predict clinical diagnosis of depression.
Conclusions: The HAPI-Infant is a novel, psychometrically strong diagnostic tool suitable for recognizing anhedonia during the first year of life with strong predictive value for later depressive symptoms. In view of the emerging recognition of increasing prevalence of affective disorders in children and adolescents, the importance of the HAPI-Infant in diagnosing anhedonia is encouraging. Early recognition of anhedonia could target high-risk individuals for intervention and perhaps prevention of mental health disorders.
Competing Interests: Declaration of competing interest The authors have nothing to disclose.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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