Factors associated with improved health-related quality of life due to improvements in physical function and dialysis-related symptoms following intradialytic exercise in outpatients undergoing haemodialysis.

Autor: Takahashi R; Department of Rehabilitation, Kaikoukai Josai Hospital, Nagoya, Aichi, Japan. 16RP24@g.seirei.ac.jp.; Division of Rehabilitation Science, Seirei Christopher University Graduate School, Hamamatsu, Shizuoka, Japan. 16RP24@g.seirei.ac.jp., Yabe H; Department of Physical Therapy, School of Rehabilitation Sciences, Seirei Christopher University, Hamamatsu, Shizuka, Japan., Ishikawa H; Department of Internal Medicine, Kaikoukai Josai Hospital, Nagoya, Aichi, Japan., Hibino T; Department of Rehabilitation, Kaikoukai Josai Hospital, Nagoya, Aichi, Japan., Morishita S; Department of Rehabilitation, Kaikoukai Josai Hospital, Nagoya, Aichi, Japan., Kono K; Department of Physical Therapy, International University of Health and Welfare School of Health Science at Narita, Narita, Chiba, Japan., Moriyama Y; Department of Wellness Center, Nagoya Kyoritsu Hospital, Nagoya, Aichi, Japan., Yamada T; Dialysis Division, Kaikoukai Healthcare Group, Nagoya, Aichi, Japan.
Jazyk: angličtina
Zdroj: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation [Qual Life Res] 2024 Apr; Vol. 33 (4), pp. 1133-1142. Date of Electronic Publication: 2024 Jan 23.
DOI: 10.1007/s11136-023-03593-w
Abstrakt: Purpose: Exercise therapy is a crucial intervention for improving health-related quality of life (HRQOL) in patients undergoing haemodialysis. However, factors that improve HRQOL by improving physical function and dialysis-related symptoms remain unknown. This study aimed to examine the physical function parameters and dialysis-related symptoms that improve HRQOL following intradialytic exercise.
Methods: This multicentre cohort study included 596 patients who participated in an intradialytic exercise program three times per week for a period of 6 months, which comprised of stretching and resistance training. EuroQol 5 dimensions 5-level (EQ5D-5L), grip strength, isometric knee extension strength, 10-m walking speed, Short Physical Performance Battery (SPPB), and improvement in dialysis-related symptoms were measured at the baseline and post-intervention. A linear mixed model was used to analyse the effects of improved physical function and dialysis-related symptoms on improvements in EQ5D-5L.
Results: As a physical function index affecting ΔEQ5D-5L, only SPPB showed a significant increase in ΔEQ5D-5L compared with the non-improved group [difference in ΔEQ5D-5L, 0.05 (0.004 to 0.092) point; p < 0.05]). In addition, dialysis-related symptoms with Improved physical conditions [difference in ΔEQ5D-5L, 0.07 (0.02 to 0.13) point] and an Extended walking distance [difference in ΔEQ5D-5L was 0.07 (0.01 to 0.12) point] significantly influenced ΔEQ5D-5L (p < 0.05, both).
Conclusions: The improvements observed in the SPPB scores and self-percieved physical fitness and ambulation range, attributable to intradialytic exercise, may potentially improve HRQOL.
(© 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
Databáze: MEDLINE
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