Endoscopy in pediatric polyposis syndromes: why, when and how.

Autor: Cohen S; Pediatric Gastroenterology Institute, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, affiliated to the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Hyer W; St Mark's Hospital Polyposis Registry, Harrow, UK., Attard T; Division of Gastroenterology, Hepatology and Nutrition, The University of Missouri in Kansas Division of Gastroenterology, Hepatology and Nutrition, City School of Medicine, Children's Mercy Hospital Kansas City, Missouri, USA.
Jazyk: angličtina
Zdroj: European journal of gastroenterology & hepatology [Eur J Gastroenterol Hepatol] 2024 Mar 01; Vol. 36 (3), pp. 255-263. Date of Electronic Publication: 2024 Jan 10.
DOI: 10.1097/MEG.0000000000002702
Abstrakt: Single or multiple polyps are frequently encountered during colonoscopy among children and adolescents and may be indicative of hereditary polyposis syndrome (HPS). The management of children with single or multiple polyps is guided by the number of polyps, their distribution and the histological findings. Children with HPS carry a high risk of complications, including intestinal and extra-intestinal malignancies. The goals of surveillance in pediatric HPS are to treat symptoms, monitor the burden of polyps and prevent short- and long-term complications. Therefore, the management of children with HPS is based on therapeutic endoscopy. The strategy of therapeutic endoscopy is a careful assessment and characterization of the polyps and performing polypectomies using advanced endoscopic techniques. A multidisciplinary approach, comprising clinical, interventional endoscopy, cancer surveillance and support of familial and emotional aspects is essential in the management of children with HPS.
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Databáze: MEDLINE