Clinical characteristics of hospitalized male adolescents and young adults with atypical anorexia nervosa.

Autor: Nagata JM; Department of Pediatrics, University of California, San Francisco, California, USA., Vargas R; Department of Pediatrics, University of California, San Francisco, California, USA., Sanders AE; Department of Pediatrics, University of California, San Francisco, California, USA., Stuart E; Department of Pediatrics, University of California, San Francisco, California, USA., Downey AE; Department of Pediatrics, University of California, San Francisco, California, USA.; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA., Chaphekar AV; Department of Pediatrics, University of California, San Francisco, California, USA., Nguyen A; Department of Pediatrics, University of California, San Francisco, California, USA., Ganson KT; Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada., Buckelew SM; Department of Pediatrics, University of California, San Francisco, California, USA., Garber AK; Department of Pediatrics, University of California, San Francisco, California, USA.
Jazyk: angličtina
Zdroj: The International journal of eating disorders [Int J Eat Disord] 2024 Apr; Vol. 57 (4), pp. 1008-1019. Date of Electronic Publication: 2024 Jan 11.
DOI: 10.1002/eat.24132
Abstrakt: Objective: To describe the clinical characteristics of male adolescents and young adults hospitalized for medical complications of atypical anorexia nervosa (atypical AN) and to compare their clinical characteristics with females with atypical AN and males with anorexia nervosa (AN).
Method: A retrospective review of electronic medical records for patients with atypical AN and AN aged 9-25 admitted to the UCSF Eating Disorders Program from May 2012 to August 2020 was conducted.
Results: Among 21 males with atypical AN (mean age 15.1 ± 2.7, mean %mBMI 102.0 ± 11.8), medical complications evidenced by admission laboratory values included anemia (52.9%), vitamin D insufficiency/deficiency (52.6%), and zinc deficiency (31.6%). Compared with females with atypical AN (n = 69), males with atypical AN had longer length of stay (11.4 vs 8.4 days, p = .004), higher prescribed kcal at discharge (4114 vs 3045 kcal, p < .001), lower heart rate nadir (40.0 vs 45.8, p = .038), higher aspartate transaminase (AST, 37.9 vs 26.2 U/L, p = .032), higher alanine transaminase (ALT, 30.6 vs 18.3 U/L, p = .005), and higher rates of anemia (52.9% vs 19.4%, p = .005), with no differences in vitamin D, zinc, and vital signs. Compared with males with AN (n = 40), males with atypical AN had no significant differences in vital signs or laboratory assessments during the hospitalization.
Discussion: Atypical AN in males leads to significant medical comorbidity, and males with atypical AN require longer hospital stays compared to females with atypical AN. Rates of abnormal vital signs and abnormal serum laboratory values during hospital admissions do not differ in males with atypical AN compared to AN.
Public Significance: Adolescent and young adult males with atypical anorexia nervosa experience significant medical complications. Males with atypical anorexia nervosa had longer hospitalizations and higher prescribed nutrition at discharge than females. Medical complications of atypical anorexia nervosa in male adolescents and young adults were generally equal to those of male adolescents and young adults with anorexia nervosa. Clinicians should be aware of unique medical complications of males with atypical anorexia nervosa.
(© 2024 The Authors. International Journal of Eating Disorders published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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