Hypoxic peripheral chemoreflex stimulation-dependent cardiorespiratory coupling is decreased in swimmer athletes.

Autor: Andrade DC; Exercise Applied Physiology Laboratory, Centro de Investigación en Fisiología y Medicina de Altura (FIMEDALT), Departamento Biomedico, Facultad de Ciencias de la Salud, Universidad de Antofagasta, Antofagasta, Chile., Arce-Álvarez A; Escuela de Kinesiología, Facultad de Odontología y Ciencias de la Rehabilitación, Universidad San Sebastián, Santiago, Chile., Salazar-Ardiles C; Exercise Applied Physiology Laboratory, Centro de Investigación en Fisiología y Medicina de Altura (FIMEDALT), Departamento Biomedico, Facultad de Ciencias de la Salud, Universidad de Antofagasta, Antofagasta, Chile.; Navarrabiomed, Hospital Universitario de Navarra (UHN), Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, Navarra, Spain., Toledo C; Laboratory of Cardiorespiratory and Sleep Physiology. Institute of Physiology. Faculty of Medicine, Universidad Austral de Chile, Valdivia, Chile., Guerrero-Henriquez J; Centro de Investigación en Fisiología y Medicina de Altura (FIMEDALT), Departamento de Ciencias de la Rehabilitación y el Movimiento Humano, Facultad de Ciencias de la Salud, Universidad de Antofagasta, Antofagasta, Chile., Alvarez C; Exercise and Rehabilitation Sciences Institute, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago, Chile., Vasquez-Muñoz M; Dirección de Docencia de Especialidades Médicas, Dirección de Postgrado, Facultad de Medicina y Ciencias de la Salud, Universidad Mayor, Santiago, Chile., Izquierdo M; Navarrabiomed, Hospital Universitario de Navarra (UHN), Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, Navarra, Spain., Millet GP; Institute of Sport Sciences, University of Lausanne, Lausanne, Switzerland.
Jazyk: angličtina
Zdroj: Physiological reports [Physiol Rep] 2024 Jan; Vol. 12 (1), pp. e15890.
DOI: 10.14814/phy2.15890
Abstrakt: Swimmer athletes showed a decreased ventilatory response and reduced sympathetic activation during peripheral hypoxic chemoreflex stimulation. Based on these observations, we hypothesized that swimmers develop a diminished cardiorespiratory coupling due to their decreased hypoxic peripheral response. To resolve this hypothesis, we conducted a study using coherence time-varying analysis to assess the cardiorespiratory coupling in swimmer athletes. We recruited 12 trained swimmers and 12 control subjects for our research. We employed wavelet time-varying spectral coherence analysis to examine the relationship between the respiratory frequency (R f ) and the heart rate (HR) time series during normoxia and acute chemoreflex activation induced by five consecutive inhalations of 100% N 2 . Comparing swimmers to control subjects, we observed a significant reduction in the hypoxic ventilatory responses to N 2 in swimmers (0.012 ± 0.001 vs. 0.015 ± 0.001 ΔV E /ΔVO 2 , and 0.365 ± 0.266 vs. 1.430 ± 0.961 ΔV E /ΔVCO 2 /ΔSpO 2 , both p < 0.001, swimmers vs. control, respectively). Furthermore, the coherence at the LF cutoff during hypoxia was significantly lower in swimmers compared to control subjects (20.118 ± 3.502 vs. 24.935 ± 3.832 area under curve [AUC], p < 0.012, respectively). Our findings strongly indicate that due to their diminished chemoreflex control, swimmers exhibited a substantial decrease in cardiorespiratory coupling during hypoxic stimulation.
(© 2024 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.)
Databáze: MEDLINE
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