[Hypogonadism syndrome in men with inflammatory joint diseases: A review].

Autor: Panevin TS; Nasonova Research Institute of Rheumatology., Rozhivanov RV; National Medical Research Center for Endocrinology., Nasonov EL; Nasonova Research Institute of Rheumatology.
Jazyk: ruština
Zdroj: Terapevticheskii arkhiv [Ter Arkh] 2023 Jul 16; Vol. 95 (5), pp. 429-434. Date of Electronic Publication: 2023 Jul 16.
Abstrakt: Most rheumatic diseases are characterized by sexual dimorphism both in prevalence and in the characteristics of the clinical course. Increased production of pro-inflammatory cytokines that accompanies inflammatory joint diseases may be accompanied by a decrease in the level of male sex hormones, and vice versa, the presence of hypogonadism in men increases the risk of developing certain rheumatic diseases. The review presents data on the relationship between testosterone deficiency and major inflammatory joint diseases, as well as the effect of testosterone replacement therapy on their manifestations.
Databáze: MEDLINE