Safety and Efficacy of Cervical Ripening and Induction of Labor Using Prostaglandin E1 in Primiparas, Multiparas and Grand Multiparas.

Autor: Kashani-Ligumsky L; Department of Obstetrics and Gynecology, Maaynei Hayeshua Medical Center, Bnei Brak, Israel.; Sackler School of Medicine, Tel Aviv university, Tel Aviv, Israel., Bilgory A; IVF Unit, Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Hadera, Israel.; Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, 3109601 Israel., Neiger R; Department of Obstetrics and Gynecology, University of South Carolina, Columbia, South Carolina USA.
Jazyk: angličtina
Zdroj: Journal of obstetrics and gynaecology of India [J Obstet Gynaecol India] 2023 Dec; Vol. 73 (Suppl 2), pp. 222-226. Date of Electronic Publication: 2023 Nov 15.
DOI: 10.1007/s13224-023-01847-8
Abstrakt: Objective: To compare the efficacy and safety of cervical ripening and induction of labor with prostaglandin E1 among primiparas, multiparas and grand multiparas.
Study Design: This was a retrospective cohort study.
Results: Between January and December 2017, 1713 women underwent cervical ripening and induction of labor with prostaglandin E1: 523 were primiparas, 656 were multiparas, and 534 were grand multiparas. Four hundred and seventy-nine (91.6%) primiparas delivered vaginally as did 640 (97.6%) multiparas and 521 (97.6%) grand multiparas. Forty-four (8.4%) primiparas underwent cesarean delivery compared to 16 (2.4%) multiparas and 13(2.4%) grand multiparas. Induction to delivery interval was significantly longer in primiparas (29.7 ± 22.8 h). There were no cases of uterine rupture, and the rates of postpartum hemorrhage and endometritis were similar among the three groups. Neonatal outcomes including Apgar score < 7 and umbilical artery pH < 7.1 were not significantly different between the groups.
Conclusion: Using prostaglandin E1 for cervical ripening and labor induction is efficient and safe in primiparas, multiparas and grand multiparas.
Competing Interests: Conflict of interestThe authors declare that they have no competing interests.
(© Federation of Obstetric & Gynecological Societies of India 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
Databáze: MEDLINE
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