Tissue-Tracking Mitral Annular Displacement in Neonates: A Novel Index of Left Ventricular Systolic Function.

Autor: Ficial B; Neonatal Intensive Care Unit, University and Hospital Trust of Verona, Verona, Italy., Benfari G; Section of Cardiology, Department of Medicine, University of Verona, Verona, Italy., Bonafiglia E; Neonatal Intensive Care Unit, University and Hospital Trust of Verona, Verona, Italy., Clemente M; Neonatal Intensive Care Unit, University and Hospital Trust of Verona, Verona, Italy., Cappelleri A; Neonatal Intensive Care Unit, University and Hospital Trust of Verona, Verona, Italy., Flore AI; Neonatal Intensive Care Unit, University and Hospital Trust of Verona, Verona, Italy., Petoello E; Neonatal Intensive Care Unit, University and Hospital Trust of Verona, Verona, Italy., Ciarcià M; Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy., Nogara S; Neonatal Intensive Care Unit, University and Hospital Trust of Verona, Verona, Italy., Milocchi C; Neonatal Intensive Care Unit, University and Hospital Trust of Verona, Verona, Italy., Dani C; Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy., Ribichini FL; Section of Cardiology, Department of Medicine, University of Verona, Verona, Italy., Gottin L; Intensive Care Unit, Department of Surgery, Dentistry, Maternity and Infant, University and Hospital Trust of Verona, Verona, Italy., Corsini I; Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.
Jazyk: angličtina
Zdroj: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine [J Ultrasound Med] 2024 Apr; Vol. 43 (4), pp. 729-739. Date of Electronic Publication: 2023 Dec 22.
DOI: 10.1002/jum.16399
Abstrakt: Objectives: To assess the feasibility, accuracy, and reproducibility of tissue-tracking mitral annular displacement (TMAD) compared with other measures of left ventricular systolic function in healthy preterm and term neonates in the transitional period.
Methods: This was a prospective observational study. Two echocardiograms were performed at 24 and 48 hours of life. TMAD, shortening fraction (SF), ejection fraction (EF), s', and global longitudinal strain (GLS) were measured offline. Accuracy to detect impaired GLS was tested by ROC curve analysis. DeLong test was used to compare AUCs. Intra and interobserver reproducibility of the off-line analysis was calculated.
Results: Mean ± SD gestational age and weight were 34.2 ± 3.8 weeks and 2162 ± 833 g, respectively. TMAD was feasible in 168/180 scans (93%). At 24 hours the AUC (95% CI) of SF, EF, s', and TMAD (%) was 0.51 (0.36-0.67), 0.68 (0.54-0.82), 0.63 (0.49-0.77), and 0.89 (0.79-0.99) respectively. At 48 hours the AUC (95% CI) of SF, EF, s', and TMAD (%) was 0.64 (0.51-0.77), 0.59 (0.37-0.80), 0.70 (0.54-0.86), and 0.96 (0.91-1.00), respectively. The AUC of TMAD was superior to the AUC of SF, EF, s', at both timepoints (P < .02). Intraclass correlation coefficients (95% CI) of intra and interobserver reproducibility of TMAD were 0.97 (0.95-0.99) and 0.94 (0.88-0.97), respectively.
Conclusion: TMAD showed improved accuracy and optimal reproducibility in neonates in the first 48 hours of life.
(© 2023 American Institute of Ultrasound in Medicine.)
Databáze: MEDLINE
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