Contact allergies to dental materials in patients.

Autor:	Forkel S; Department of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany., Schubert S; Information Network of Departments of Dermatology, Institute at the University Medical Center Göttingen, Göttingen, Germany., Corvin L; Department of Dermatology, Venereology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany., Heine G; Department of Dermatology, Venereology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany., Lang CCV; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Oppel E; Department of Dermatology and Allergy, LMU University Hospital, LMU Munich, Munich, Germany., Pföhler C; Department of Dermatology, Saarland University Medical School, Homburg, Germany., Treudler R; Department of Dermatology, Venereology and Allergology, University Medical Center, Leipzig, Germany., Bauer A; Department of Dermatology, University Allergy Center, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany., Sulk M; Department of Dermatology, University Hospital Münster, Münster, Germany., Kränke B; Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria., Schäkel K; Department of Dermatology, Ruprecht Karls University, Heidelberg, Germany., Heratizadeh A; Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany., Worm M; Division of Allergy and Immunology, Department of Dermatology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Witte J; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Geier J; Information Network of Departments of Dermatology, Institute at the University Medical Center Göttingen, Göttingen, Germany.; Lower Saxony Institute of Occupational Dermatology, University of Göttingen, Göttingen, Germany., Buhl T; Department of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany.; Lower Saxony Institute of Occupational Dermatology, University of Göttingen, Göttingen, Germany.
Jazyk:	angličtina
Zdroj:	The British journal of dermatology [Br J Dermatol] 2024 May 17; Vol. 190 (6), pp. 895-903.
DOI:	10.1093/bjd/ljad525
Abstrakt:	Background: Concerns regarding contact allergies and intolerance reactions to dental materials are widespread among patients. Development of novel dental materials and less frequent amalgam use may alter sensitization profiles in patients with possible contact allergy. Objectives: To analyse current sensitization patterns to dental materials in patients with suspected contact allergy. Methods: This retrospective, multicentre analysis from the Information Network of Departments of Dermatology (IVDK) selected participants from 169 834 people tested in 2005-2019 and registered with (i) an affected area of 'mouth' (and 'lips'/'perioral'), (ii) with the dental material in question belonging to one of three groups (dental filling materials, oral implants or dentures or equivalents) and (iii) with patch-testing done in parallel with the German baseline series, (dental) metal series and dental technician series. Results: A total of 2730 of 169 834 tested patients met the inclusion criteria. The patients were predominantly women (81.2%) aged ≥ 40 years (92.8%). The sensitization rates with confirmed allergic contact stomatitis in women (n = 444) were highest for metals (nickel 28.6%, palladium 21.4%, amalgam 10.9%), (meth)acrylates [2-hydroxyethyl methacrylate (HEMA) 4.8%] and the substances propolis (6.8%) and 'balsam of Peru' (11.4%). The most relevant acrylates were HEMA, 2-hydroxypropyl methacrylate, methyl methacrylate, ethylene glycol dimethacrylate and pentaerythritol triacrylate. Few men were diagnosed with allergic contact stomatitis (n = 68); sensitization rates in men were highest for propolis (14.9%) and amalgam (13.6%). Conclusions: Allergic contact stomatitis to dental materials is rare. Patch testing should not only focus on metals such as nickel, palladium, amalgam and gold, but also (meth)acrylates and the natural substances propolis and 'balsam of Peru'. Competing Interests: Conflicts of interest The authors declare no conflicts of interest. (© The Author(s) 2023. Published by Oxford University Press on behalf of British Association of Dermatologists. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
Databáze:	MEDLINE
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