Remimazolam Sedation and Neuraxial Anesthesia in a Patient with Amyotrophic Lateral Sclerosis Undergoing an Open Colectomy: A Case Report.

Autor:	Nimma S; From the Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Jacksonville, Florida., Gans A; From the Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Jacksonville, Florida., Wardhan R; Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida., Allen W; From the Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Jacksonville, Florida.
Jazyk:	angličtina
Zdroj:	A&A practice [A A Pract] 2023 Dec 18; Vol. 17 (12), pp. e01733. Date of Electronic Publication: 2023 Dec 18 (Print Publication: 2023).
DOI:	10.1213/XAA.0000000000001733
Abstrakt:	Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease involving the upper and lower motor neurons. Perioperative management of patients with ALS can be challenging due to the risk of hemodynamic instability, aspiration, and ventilatory failure. We discuss a 58-year-old male patient with ALS who underwent open abdominal surgery under regional anesthesia utilizing a remimazolam infusion for sedation. While various sedation agents have been used successfully in patients with ALS, remimazolam, a new short-acting benzodiazepine with unique pharmacologic properties and reversible anxiolysis, provides amnesia while avoiding ventilatory depression. Competing Interests: The authors declare no conflicts of interest. (Copyright © 2023 International Anesthesia Research Society.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu