Obesity and Miscarriage.
| Autor: | McLean S; Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Boots CE; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois. |
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| Jazyk: | angličtina |
| Zdroj: | Seminars in reproductive medicine [Semin Reprod Med] 2023 Jul; Vol. 41 (3-04), pp. 80-86. Date of Electronic Publication: 2023 Dec 15. |
| DOI: | 10.1055/s-0043-1777759 |
| Abstrakt: | Obesity affects nearly 40% of reproductive-aged women and has serious implications for women's overall and reproductive health. Women with an elevated body mass index (BMI) have higher rates of anovulation and irregular menses, lower success with fertility treatment, and significantly higher rates of pregnancy complications, such as hypertension/preeclampsia, gestational diabetes, and preterm delivery. Many studies have also shown an association between obesity and early pregnancy loss. However, the causal association between BMI and miscarriage has not been elucidated, likely due to the multifactorial effects that BMI may have on early pregnancy development. In addition, BMI as an isolated variable fails to capture other relevant confounding health risk factors, such as nutrition, physical activity, and insulin resistance. In this review, we will summarize the current literature demonstrating the association between BMI and miscarriage, highlight the research that attempts to explain the association, and finally provide data on therapeutic interventions to improve reproductive outcomes in women suffering from obesity and early pregnancy loss. Competing Interests: Disclosure The authors report no conflicts of interest in this work. (Thieme. All rights reserved.) |
| Databáze: | MEDLINE |
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