Factors affecting corneal deformation amplitude measured by Corvis ST in eyes with open-angle glaucoma.

Autor: Pradhan ZS; Department of Glaucoma, Narayana Nethralaya, Bangalore, Karnataka, India., Sreenivasaiah S; Department of Glaucoma, Narayana Nethralaya, Bangalore, Karnataka, India., Deshmukh S; Department of Glaucoma, Narayana Nethralaya, Bangalore, Karnataka, India., Mangala L; Department of Glaucoma, Narayana Nethralaya, Bangalore, Karnataka, India., Shroff S; Department of Glaucoma, Narayana Nethralaya, Bangalore, Karnataka, India., Devi S; Department of Glaucoma, Narayana Nethralaya, Bangalore, Karnataka, India., Webers CA; Department of Glaucoma, University Eye Clinic Maastricht, University Medical Center, Maastricht, The Netherlands., Rao HL; Department of Glaucoma, University Eye Clinic Maastricht, University Medical Center, Maastricht, The Netherlands.; Department of Glaucoma, Narayana Nethralaya, 63, Bannerghatta Road, Hulimavu, Bangalore, Karnataka, India.
Jazyk: angličtina
Zdroj: Indian journal of ophthalmology [Indian J Ophthalmol] 2024 Apr 01; Vol. 72 (4), pp. 533-537. Date of Electronic Publication: 2023 Dec 15.
DOI: 10.4103/IJO.IJO_822_23
Abstrakt: Purpose: To evaluate the factors affecting corneal deformation amplitude (DA) measured using Corvis ST in eyes with open-angle glaucoma.
Methods: This prospective, longitudinal study included 48 eyes with open-angle glaucoma who required additional intraocular pressure (IOP)-lowering drops. All eyes underwent a complete eye examination at baseline, including a Corvis ST, which was repeated 4-8 weeks after the change in therapy. Factors affecting the corneal biomechanics, namely the DA, were determined using mixed effect models.
Results: The mean age of the cohort was 65.0 ± 7.9 years. The mean IOP reduced from 23.4 ± 5.4 mmHg to 17.9 ± 5 mmHg after the change in glaucoma treatment ( P < 0.001). The DA increased from 0.89 ± 0.16 mm to 1.00 ± 0.13 mm after IOP reduction ( P < 0.001). On mixed effect model analysis, IOP (-0.02 ± 0.001, P < 0.001) and corneal pachymetry (-0.0003 ± 0.0001, P = 0.02) affected the change in the DA.
Conclusion: IOP and corneal pachymetry affect the DA and must be accounted for when using Corvis ST to evaluate corneal biomechanics in glaucoma.
(Copyright © 2023 Copyright: © 2023 Indian Journal of Ophthalmology.)
Databáze: MEDLINE
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