An ANI gap within bacterial species that advances the definitions of intra-species units.

Autor:	Rodriguez-R LM; Department of Microbiology, and Digital Science Center (DiSC), University of Innsbruck, Innsbruck, Austria., Conrad RE; School of Civil and Environmental Engineering, and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Viver T; Department of Animal and Microbial Biodiversity, Marine Microbiology Group, Mediterranean Institutes for Advanced Studies (IMEDEA, CSIC-UIB), Esporles, Spain., Feistel DJ; School of Civil and Environmental Engineering, and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Lindner BG; School of Civil and Environmental Engineering, and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Venter SN; Department of Biochemistry, Genetics and Microbiology, and Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Pretoria, South Africa., Orellana LH; Department of Molecular Ecology, Max Planck Institute for Marine Microbiology, Bremen, Germany., Amann R; Department of Molecular Ecology, Max Planck Institute for Marine Microbiology, Bremen, Germany., Rossello-Mora R; Department of Animal and Microbial Biodiversity, Marine Microbiology Group, Mediterranean Institutes for Advanced Studies (IMEDEA, CSIC-UIB), Esporles, Spain., Konstantinidis KT; School of Civil and Environmental Engineering, and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Jazyk:	angličtina
Zdroj:	MBio [mBio] 2024 Jan 16; Vol. 15 (1), pp. e0269623. Date of Electronic Publication: 2023 Dec 12.
DOI:	10.1128/mbio.02696-23
Abstrakt:	Importance: Bacterial strains and clonal complexes are two cornerstone concepts for microbiology that remain loosely defined, which confuses communication and research. Here we identify a natural gap in genome sequence comparisons among isolate genomes of all well-sequenced species that has gone unnoticed so far and could be used to more accurately and precisely define these and related concepts compared to current methods. These findings advance the molecular toolbox for accurately delineating and following the important units of diversity within prokaryotic species and thus should greatly facilitate future epidemiological and micro-diversity studies across clinical and environmental settings. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu