Evaluating and benchmarking the EEG signal quality of high-density, dry MXene-based electrode arrays against gelled Ag/AgCl electrodes.

Autor:	Erickson B; Applied Cognitive and Brain Sciences, Department of Psychology, Drexel University, Philadelphia, PA 19104, United States of America., Rich R; Applied Cognitive and Brain Sciences, Department of Psychology, Drexel University, Philadelphia, PA 19104, United States of America., Shankar S; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, United States of America.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, United States of America.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, United States of America., Kim B; Applied Cognitive and Brain Sciences, Department of Psychology, Drexel University, Philadelphia, PA 19104, United States of America., Driscoll N; Laboratory of Electronics Research, Massachusetts Institute of Technology, Cambridge, MA 02139, United States of America., Mentzelopoulos G; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, United States of America.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, United States of America.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, United States of America., Fernandez-Nuñez G; Applied Cognitive and Brain Sciences, Department of Psychology, Drexel University, Philadelphia, PA 19104, United States of America., Vitale F; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, United States of America.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, United States of America.; Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, United States of America.; Department of Physical Medicine and Rehabilitation, University of Pennsylvania, Philadelphia, PA 19104, United States of America., Medaglia JD; Applied Cognitive and Brain Sciences, Department of Psychology, Drexel University, Philadelphia, PA 19104, United States of America.; Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, United States of America.; Department of Neurology, Drexel University, Philadelphia, PA 19104, United States of America.
Jazyk:	angličtina
Zdroj:	Journal of neural engineering [J Neural Eng] 2024 Jan 12; Vol. 21 (1). Date of Electronic Publication: 2024 Jan 12.
DOI:	10.1088/1741-2552/ad141e
Abstrakt:	Objective. To evaluate the signal quality of dry MXene-based electrode arrays (also termed 'MXtrodes') for electroencephalographic (EEG) recordings where gelled Ag/AgCl electrodes are a standard. Approach. We placed 4 × 4 MXtrode arrays and gelled Ag/AgCl electrodes on different scalp locations. The scalp was cleaned with alcohol and rewetted with saline before application. We recorded from both electrode types simultaneously while participants performed a vigilance task. Main results. The root mean squared amplitude of MXtrodes was slightly higher than that of Ag/AgCl electrodes (.24-1.94 uV). Most MXtrode pairs had slightly lower broadband spectral coherence (.05 to .1 dB) and Delta- and Theta-band timeseries correlation (.05 to .1 units) compared to the Ag/AgCl pair ( p < .001). However, the magnitude of correlation and coherence was high across both electrode types. Beta-band timeseries correlation and spectral coherence were higher between neighboring MXtrodes in the array (.81 to .84 units) than between any other pair (.70 to .75 units). This result suggests the close spacing of the nearest MXtrodes (3 mm) more densely sampled high spatial-frequency topographies. Event-related potentials were more similar between MXtrodes ( ρ ⩾ .95) than equally spaced Ag/AgCl electrodes ( ρ ⩽ .77, p < .001). Dry MXtrode impedance ( x̄ = 5.15 KΩ cm 2 ) was higher and more variable than gelled Ag/AgCl electrodes ( x̄ = 1.21 KΩ cm 2 , p < .001). EEG was also recorded on the scalp across diverse hair types. Significance. Dry MXene-based electrodes record EEG at a quality comparable to conventional gelled Ag/AgCl while requiring minimal scalp preparation and no gel. MXtrodes can record independent signals at a spatial density four times higher than conventional electrodes, including through hair, thus opening novel opportunities for research and clinical applications that could benefit from dry and higher-density configurations. (Creative Commons Attribution license.)
Databáze:	MEDLINE
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