Investigation of the Relationship Between Laparoscopic Sleeve Gastrectomy and Gastroesophageal Reflux Disease Using 24-hour Multichannel Intraluminal Impedance With pH Testing According to Current Consensus.

Autor:	Teke E; Departments of General Surgery., Esen Bulut N; Departments of General Surgery., Onur E; Departments of General Surgery., Güneş Y; Departments of General Surgery., Fersahoglu MM; Departments of General Surgery., Ergin A; Departments of General Surgery., Taşdelen İ; Departments of General Surgery., Köroğlu M; Gastroenterology, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey., Çavuş B; Istanbul University Istanbul Medical Faculty/Gastroenterohepatology Department, İstanbul University, İstanbul Medical School, Turgut Özal Millet Street, Fatih/İstanbul., Akyüz Ü; Gastroenterology, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey., Akyüz F; Istanbul University Istanbul Medical Faculty/Gastroenterohepatology Department, İstanbul University, İstanbul Medical School, Turgut Özal Millet Street, Fatih/İstanbul.
Jazyk:	angličtina
Zdroj:	Surgical laparoscopy, endoscopy & percutaneous techniques [Surg Laparosc Endosc Percutan Tech] 2024 Feb 01; Vol. 34 (1), pp. 9-13. Date of Electronic Publication: 2024 Feb 01.
DOI:	10.1097/SLE.0000000000001253
Abstrakt:	Background: Laparoscopic sleeve gastrectomy (LSG) is a popular weight loss procedure with potential effects on gastroesophageal reflux disease (GERD). However, research on the association between LSG and GERD using objective evaluation criteria, such as multichannel intraluminal impedance combined with pH testing (MII-pH), is limited. This study aimed to investigate the impact of LSG on GERD using MII-pH and current consensus guidelines. Materials and Methods: It was conducted as a prospective clinical study on 33 patients who underwent LSG between January 2022 and August 2022. MII-pH and high-resolution manometry were performed preoperatively and 3 to 6 months postoperatively. GERD diagnosis was based on MII-pH results using the Lyon and Update Porto consensus guidelines. Results: Postoperative MII-pH analysis revealed a significant increase in acid reflux time, acid exposure time, reflux index, esophageal clearance, total reflux time, and longest reflux period. Weak acid reflux episodes decreased, while Demeester score and alkaline reflux showed nonsignificant increases. Pathologic reflux significantly increased postoperatively based on MII-pH diagnosis. High-resolution manometry showed a significant increase in unsuccessful motility. Conclusion: Although the Demeester score calculation consists of 6 metrics, including acid exposure time, the acid exposure time is more specific in detecting pathologic reflux. Pathologic GERD increases significantly with LSG in the early period. Therefore, preoperative and postoperative endoscopy and MII-pH can provide valuable information regarding the need for closer follow-up after LSG. Competing Interests: The authors declare no conflicts of interest. (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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