Contemporary Outcomes of Transduodenal Sphincteroplasty: the Importance of Surgical Quality.

Autor: Walia S; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA., Zaidi MY; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA., McGuire S; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA., Milam C; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA., Fogel EL; Division of Gastroenterology/Hepatology, Department of Medicine, Indiana University Medical Center, 550 N. University Boulevard, UH 4100, Indianapolis, IN, 46202, USA., Sherman S; Division of Gastroenterology/Hepatology, Department of Medicine, Indiana University Medical Center, 550 N. University Boulevard, UH 4100, Indianapolis, IN, 46202, USA., Lehman G; Division of Gastroenterology/Hepatology, Department of Medicine, Indiana University Medical Center, 550 N. University Boulevard, UH 4100, Indianapolis, IN, 46202, USA., Pitt HA; Department of Surgery, Robert Wood Johnson Medical School and Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ, 08903, USA., Nakeeb A; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA., Schmidt CM; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA., House MG; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA., Ceppa EP; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA., Timsina L; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA., Zyromski NJ; Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr, Emerson Hall 519, Indianapolis, IN, 46202, USA. nzyromsk@iupui.edu.
Jazyk: angličtina
Zdroj: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract [J Gastrointest Surg] 2023 Dec; Vol. 27 (12), pp. 2885-2892. Date of Electronic Publication: 2023 Dec 07.
DOI: 10.1007/s11605-022-05539-y
Abstrakt: Background: Sphincter of Oddi dysfunction (SOD) is managed primarily by endoscopic sphincterotomy (ES); however, surgical transduodenal sphincteroplasty (TDS) is a treatment option for select patients. In our high-volume pancreatico-biliary practice, we have observed variable outcomes among TDS patients; therefore, we sought to determine preoperative predictors of durable improvement in quality of life.
Methods: SOD patients treated by TDS between January 2006 and December 2015 were studied. The primary outcome measure was long-term changes in quality of life after sphincteroplasty. The secondary outcome measure examined postoperative outcomes, including postoperative complications, need for repeat procedures, and readmission rates. Perioperative data were abstracted, and the SF-36 quality-of-life (QoL) survey was administered. Standard statistical analysis included non-parametric methods to examine bivariate associations.
Results: Eighty-eight patients had an average follow-up duration of 6.7 (± 2.9) years. Thirty (34%) patients were naïve to endoscopic therapy. Patients with prior endoscopy averaged 2.1 procedures (range 1 to 13) prior to surgery. Perioperative morbidity was 27%; one postoperative death was caused by severe acute pancreatitis. Twenty-nine (33%) patients required subsequent biliary-pancreatic procedures. QoL analysis from available patients showed that 66% were improved or much improved. With multivariable analysis including SOD type and prior endoscopic instrumentation, freedom from surgical complication was the only variable that correlated significantly with a good outcome (p < 0.02).
Conclusion: Surgical transduodenal sphincteroplasty provides durable symptom management for select patients with sphincter of Oddi dysfunction. Minimizing surgical complications optimizes long-term outcomes.
(© 2023. The Society for Surgery of the Alimentary Tract.)
Databáze: MEDLINE
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