[Chordoid gliomas of the third ventricle].

Autor:	Konovalov AN; Burdenko Neurosurgical Center, Moscow, Russia., Chernov IV; Burdenko Neurosurgical Center, Moscow, Russia., Ryzhova MV; Burdenko Neurosurgical Center, Moscow, Russia., Pitskhelauri DI; Burdenko Neurosurgical Center, Moscow, Russia., Kushel YV; Priorov National Medical Research Center of Traumatology and Orthopedics, Moscow, Russia., Astafieva LI; Burdenko Neurosurgical Center, Moscow, Russia., Sharipov OI; Burdenko Neurosurgical Center, Moscow, Russia., Klochkova IS; Burdenko Neurosurgical Center, Moscow, Russia., Sidneva YG; Research Institute of Emergency Pediatric Surgery and Traumatology, Moscow, Russia., Snigireva GP; Burdenko Neurosurgical Center, Moscow, Russia., Kalinin PL; Burdenko Neurosurgical Center, Moscow, Russia.
Jazyk:	English; Russian
Zdroj:	Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] 2023; Vol. 87 (6), pp. 14-24.
DOI:	10.17116/neiro20238706114
Abstrakt:	Background: Chordoid glioma is a rare slow-growing tumor of the central nervous system. Available world experience includes no more than 200 cases (lesion of the third ventricle in absolute majority of cases). Recognition and treatment of chordoid glioma are currently difficult problems due to small incidence of this disease. Objective: To describe clinical manifestations and surgical treatment of chordoid glioma of the third ventricle considering literature data and own experience. Material and Methods: There were 12 patients (6 men and 6 women) with chordoid glioma between 2004 and 2023 (10 patients with lesion of the third ventricle, 1 - lateral ventricle, 1 - pineal region). Only patients with tumors of the third ventricle were analyzed. Results: Total and subtotal resection was performed in 1 and 3 cases, respectively. Five patients underwent partial resection, 1 patient underwent biopsy. The follow-up data were available in 7 out of 10 patients (mean 25 months). Radiotherapy was performed in 4 patients (continued tumor growth in 2 cases). One patient died. Conclusion: Chordoid glioma is a benign tumor predominantly localized in the third ventricle. Preoperative MRI and CT in some cases make it possible to suspect chordoid glioma and differentiate this tumor from craniopharyngioma, meningioma and pituitary adenoma by such signs as isointense signal in T1WI, hyper- or isointense signal in T2WI, homogeneous contrast enhancement and edema of basal ganglia in T2 FLAIR images. The only effective treatment for chordoid glioma is surgery. Total resection is often impossible or extremely dangerous due to location of tumor, large size and invasion of the third ventricle. Postoperative mental disorders and diabetes insipidus, including severe hypernatremia, are common that requires mandatory monitoring of water and electrolyte balance.
Databáze:	MEDLINE
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