Pediatric Corneal Transplantation in Uyo, Nigeria: Early Experiences.

Autor: Nkanga ED; Paediatric Ophthalmology and Strabismus Unit, Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Umana UE; Department of Ophthalmology, Marion Eye Centre, Marion, Illinois, USA., Ibanga AA; Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Nkanga ED; Department of Pediatrics, All Saints University of Medicine, Common Wealth of Dominica, Rivers State, Nigeria., Ezeh EI; Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Ani EU; Department of Ophthalmology, The Ophthalmic Specialists, Port Harcourt, Rivers State, Nigeria., Nkanga DG; Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Etim BA; Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Akpan SI; Department of Ophthalmology, University of Uyo Teaching Hospital, Uyo, Akwa Ibom State, Nigeria.
Jazyk: angličtina
Zdroj: Nigerian journal of clinical practice [Niger J Clin Pract] 2023 Nov 01; Vol. 26 (11), pp. 1772-1776. Date of Electronic Publication: 2023 Dec 04.
DOI: 10.4103/njcp.njcp_459_23
Abstrakt: Abstract: The burden of avoidable blindness from corneal disease is significantly higher where access to specialist eye care, the cost of treatment and the treatment infrastructure including eye banking, are beyond the reach of the impoverished masses. Corneal transplantation in children is challenging: it is more technically complex; patients often require multiple examinations under general anaesthesia to optimize treatment outcomes. There is also the increased risk of several complications including graft dehiscence, infection, rejection, and inappropriate patient or caregiver care. However, when successful, it restores vision. We present a report of our initial experience with penetrating keratoplasty in 2 children with blinding corneal disease in Uyo, Nigeria. Corneal transplantation history was retrieved and data (including data on age, sex, aetiology of corneal disease, indications for corneal transplantation, pre-operative and post-operative visual acuity and intraocular pressure measurements) was extracted for this report. Both patients had standard penetrating keratoplasty performed by one surgeon, under general anaesthesia. Case one was a 10-year-old male presenting with profound visual impairment from congenital hereditary endothelial dystrophy. His best corrected post-operative visual acuity was 6/24. Case two was a 3-year-old male with vision loss due to a corneal leucoma following treated herpes simplex keratitis. Post-operatively, his best corrected visual acuity improved to 6/12. Corneal graft tissue remained clear at more than 3 years of follow-up. Although amblyopia was a notable co-morbidity, corneal transplantation significantly improved their vision. Corneal banking services are advocated for in resource-limited settings where the magnitude of corneal blindness is greatest.
(Copyright © 2023 Copyright: © 2023 Nigerian Journal of Clinical Practice.)
Databáze: MEDLINE