Depressive Symptoms in Autistic Youth with Anxiety Disorders.

Autor:	Greenberg RL; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX; and., Guzick AG; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX; and.; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA., Schneider SC; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX; and., Weinzimmer SA; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX; and., Kook M; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX; and., Perozo Garcia AB; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX; and., Storch EA; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX; and.
Jazyk:	angličtina
Zdroj:	Journal of developmental and behavioral pediatrics : JDBP [J Dev Behav Pediatr] 2023 Dec 01; Vol. 44 (9), pp. e597-e603. Date of Electronic Publication: 2023 Oct 11.
DOI:	10.1097/DBP.0000000000001223
Abstrakt:	Objective: Anxiety and depression often coexist in youth and share overlapping symptomatology; however, little is known about the comorbidity of anxiety and depression in autistic youth. This study explores (1) the frequency of depressive symptoms among autistic children with clinically significant anxiety, (2) clinical variables that may be associated with elevated depressive symptoms, and (3) whether pretreatment depressive symptoms predict cognitive behavioral therapy (CBT) outcomes for anxiety. Method: Children aged 7 to 13 years (N = 87) and their parents participated in a randomized controlled trial comparing 2 versions of a parent-led, telehealth-delivered CBT program. Parents and children completed a variety of clinical assessments and self-report questionnaires before and after treatment. Results: Fifty-seven percent of the child sample reported experiencing elevated depressive symptoms while roughly 20% of parents reported elevated depressive symptoms in their child. A strong association between anxiety and depression was found. Heightened feelings of loneliness, per child report, and functional impairment, per parent report, were found to be uniquely associated with elevated depressive symptoms. Finally, depressive symptoms were not a significant predictor of CBT outcomes for anxiety. Conclusion: Findings suggest high degrees of comorbidity between anxiety and depression among autistic children and that feelings of loneliness, anxiety, and functional impairment may be early indicators of mood-related concerns. Further research is needed to determine the full extent of the association between anxiety and depression and additional options for treating depression in autistic children. Competing Interests: Dr. Guzick receives grant support from the Texas Higher Education Coordinating Board and Ream Foundation/Misophonia Research Fund. Dr. Storch reports receiving research funding to his institution from the Ream Foundation, International OCD Foundation, and NIH. He is a consultant for Brainsway and Biohaven Pharmaceuticals. He owns stock less than $5000 in NView. He receives book royalties from Elsevier, Wiley, Oxford, American Psychological Association, Guildford, Springer, Routledge, and Jessica Kingsley. Dr. Schneider has received grant support from the Texas Higher Education Coordinating Board, NIH, and the Misophonia Research Fund. The remaining authors declare no conflict of interest. (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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