Fecal microbiomes of laboratory beagles receiving antiparasitic formulations in an experimental setting.

Autor: Ottesen A; Center for Veterinary Medicine, United States Food and Drug Administration , Laurel, Maryland, USA., Kocurek B; Center for Veterinary Medicine, United States Food and Drug Administration , Laurel, Maryland, USA., Deaver C; Center for Veterinary Medicine, United States Food and Drug Administration , Laurel, Maryland, USA., Chiesa O; Center for Veterinary Medicine, United States Food and Drug Administration , Laurel, Maryland, USA., Cohen R; Center for Veterinary Medicine, United States Food and Drug Administration , Laurel, Maryland, USA., Reed E; Center for Food Safety and Applied Nutrition, United States Food and Drug Administration , College Park, Maryland, USA., Commichaux S; Center for Food Safety and Applied Nutrition, United States Food and Drug Administration , Laurel, Maryland, USA., Mammel M; Center for Food Safety and Applied Nutrition, United States Food and Drug Administration , Laurel, Maryland, USA., McDermott P; Center for Veterinary Medicine, United States Food and Drug Administration , Laurel, Maryland, USA., Strain E; Center for Food Safety and Applied Nutrition, United States Food and Drug Administration , College Park, Maryland, USA., Myers M; Center for Veterinary Medicine, United States Food and Drug Administration , Laurel, Maryland, USA.
Jazyk: angličtina
Zdroj: Microbiology resource announcements [Microbiol Resour Announc] 2024 Jan 17; Vol. 13 (1), pp. e0086023. Date of Electronic Publication: 2023 Nov 29.
DOI: 10.1128/MRA.00860-23
Abstrakt: Here, we describe the fecal microbiome of laboratory beagles in a non-invasive experiment designed to contrast in vivo versus in vitro bioequivalence in response to antiparasitic drug administration. The experiment provided a unique opportunity to evaluate metagenomic profiles of canine feces before and after anti-parasitic drug exposure.
Competing Interests: The authors declare no conflict of interest.
Databáze: MEDLINE