| Autor: |
Panagakis G; Department of Obstetrics and Gynecology, Alexandra General Hospital, University of Athens, 4-2 Lourou, 115 28 Athens, Greece., Papapanagiotou IK; Department of Obstetrics and Gynecology, Alexandra General Hospital, University of Athens, 4-2 Lourou, 115 28 Athens, Greece., Theofanakis C; Department of Obstetrics and Gynecology, Alexandra General Hospital, University of Athens, 4-2 Lourou, 115 28 Athens, Greece., Tsetsa P; Department of Obstetrics and Gynecology, Alexandra General Hospital, University of Athens, 4-2 Lourou, 115 28 Athens, Greece., Kontogeorgi A; Department of Obstetrics and Gynecology, Attikon General Hospital, University of Athens, Rimini 1, 124 62 Haidari, Greece., Thomakos N; Department of Obstetrics and Gynecology, Alexandra General Hospital, University of Athens, 4-2 Lourou, 115 28 Athens, Greece., Rodolakis A; Department of Obstetrics and Gynecology, Alexandra General Hospital, University of Athens, 4-2 Lourou, 115 28 Athens, Greece., Haidopoulos D; Department of Obstetrics and Gynecology, Alexandra General Hospital, University of Athens, 4-2 Lourou, 115 28 Athens, Greece. |
| Abstrakt: |
The authors attempt to address the importance of timely detection and management of cervical intraepithelial neoplasia (CIN) to prevent cervical cancer. The study focused on the potential of electrical impedance spectroscopy (EIS) as an adjunct to colposcopy, aiming to enhance the accuracy of identifying high-grade cervical lesions. Colposcopy, a widely used technique, exhibited variable sensitivity in detecting high-grade lesions, which relies on the expertise of the operator. The study's primary objective is to evaluate the effectiveness of combining colposcopy with EIS in detecting high-grade cervical lesions among patients initially diagnosed with low-grade CIN based on cytology. We employed a cross-sectional observational design, recruiting 101 women with abnormal cervical cytology results. The participants underwent colposcopy with acetic acid and subsequent EIS using the ZedScan device. The ZedScan results are categorized into color-coded probability levels, with red indicating the highest likelihood of high-grade squamous intraepithelial lesions (HSIL) occurrence. Results revealed that ZedScan exhibits a sensitivity rate of 89.5% and a specificity rate of 84% for detecting high-grade lesions. Colposcopy, on the other hand, recorded a sensitivity rate of 85.5% and a specificity rate of 92%. The agreement rate between ZedScan and biopsy is 79.2%, as indicated by a kappa coefficient of 0.71, while the agreement rate between colposcopy and biopsy is 74.3%, with a kappa coefficient of 0.71. |
